Results 71 to 80 of about 2,538 (294)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Optimum Currency Areas Under Inflation Targeting

open access: yesOpen Economies Review, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Røisland, Øistein, Torvik, Ragnar
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Shrinking Endogeneity of Optimum Currency Areas Criteria: Evidence from the European Monetary Union – A Beta Regression Approach. [PDF]

open access: yes
The endogeneity of optimum currency areas criteria has been widely studied since Frankel and Rose (1998) seminal paper. Literature normally suggests that there is a positive relationship between trade and business cycles correlation.
José Passos   +2 more
core  

Áreas monetárias ótimas: teoria, unificação monetária européia e aplicações para o Mercosul

open access: yesEconomia Aplicada, 1999
This paper presents a survey of the literature on optimum currency areas. The theoretical debate on the issue is exposed and the adoption of the "euro" is discussed.
Francisco Rigolon, Fabio Giambiagi
doaj  

A Search for an Optimum Currency Area Partners for Pakistan

open access: yesThe Pakistan Development Review, 2004
The Indian government has on several occasions advocated the idea that a common currency area be formed in the SAARC region. The response from other member countries has been somewhat lukewarm. They are unconvinced that the benefit of currency union establishment will outweigh the cost emanating from the abandonment of national ...
Farooq Rasheed, Javed A. Ansari
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Optimum Currency Areas in East Asia: A Structural VAR Approach [PDF]

open access: yes
Optimum Currency Area; Monetary Union; Vector autoregression; Exchange rate; East Asia Abstract: This paper assesses the empirical desirability of the East Asian economies to an alternative exchange rate arrangement (a monetary union) that can ...
Grace H.Y. Lee, M. Azali
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Optimum Currency Area Indices - How Close is the Czech Republic to the Eurozone? [PDF]

open access: yes
In this paper we provide a survey of the optimum currency area theory, estimate the degree of the explanatory power of the optimum currency area criteria, and also calculate the optimum currency area index in the case of the Czech Republic.
Lubos Komarek   +2 more
core  

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