Results 151 to 160 of about 16,578,662 (358)
Applied SciencesThis study introduces a novel approach for the multi-model analysis of complex water distribution networks (WDNs). The research focuses on designing and optimizing various WDN configurations while adhering to hydraulic constraints. Several key parameters
Mojtaba Nedaei
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Optimum Safe Hydraulic Design of Culverts
Journal of Engineering and Sustainable Development, 2008 This research aims at obtaining the "Optimum safe hydraulic design of culverts", taking into consideration the cost of excavation, bedding, material, compacted fill, hunches, protection works, and additionally involved head loss.Because of numerous ...
Abdul-Hadi A. Al-Delewy +2 more
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On the Complexity of Dynamic Mechanism Design
, 2014 We introduce a dynamic mechanism design problem in which the designer wants to offer for sale an item to an agent, and another item to the same agent at some point in the future.
Papadimitriou, Christos +3 more
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Optimum Design of Cylindrical Worm Drive
Jixie chuandong, 2016 Taking a cylindrical worm drive mechanism as the research object,the minimizing the volume of worm gear as objective function,the limit of the worm gear tooth surface contact strength,worm stiffness,number of worm threads,worm gear module and worm ...
Wang Yuandong
doaj
, 2017 In this paper, we use Kansa method for solving the system of differential equations in the area of biology. One of the challenges in Kansa method is picking out an optimum value for Shape parameter in Radial Basis Function to achieve the best result of ...
Fallah, Mohammad Kazem +2 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source