Results 161 to 170 of about 1,140,649 (309)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Optimization Design for Installation Angle of Turbodrill Blades Based on BP Neural Network and Genetic Algorithms

Shiyou jixie, 2018
In order to further improve the hydraulic performance of turbodrill, the FINE/Design 3D platform was used to optimize the rotor blade installation angle for a ø178 mm turbodrill based on BP neural network and genetic algorithm.
Tan Chunfei, Yu Ruifeng, Hao Mingzhao, Liu Bin, Yan Wenshuang   +4 more
doaj  

Optimum Design of PIλDμ Controller for an Automatic Voltage Regulator System Using Combinatorial Test Design. [PDF]

PLoS One, 2016
Ahmed BS, Sahib MA, Gambardella LM, Afzal W, Zamli KZ.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Truss sizing optimum design using a metaheuristic approach: Connected banking system. [PDF]

Heliyon
Nemati M, Zandi Y, Sabouri J.
europepmc   +1 more source

Optimum Design of Disease-modifying Trials on Alzheimer's Disease. [PDF]

Stat Biopharm Res, 2012
Xiong C, Luo J, Gao F, Chen L, Yan Y.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Optimum Design of InGaN Blue Laser Diodes with Indium-Tin-Oxide and Dielectric Cladding Layers. [PDF]

Nanomaterials (Basel)
Onwukaeme C, Ryu HY.
europepmc   +1 more source

Alternative methods for calculating sensitivity of optimized designs to problem parameters [PDF]

Optimum sensitivity is defined as the derivative of the optimum design with respect to some problem parameter, P. The problem parameter is usually fixed during optimization, but may be changed later.
Cai, H. D., Vanderplaats, G. N.
core   +1 more source