Results 121 to 130 of about 13,905,601 (245)

HIV genotypic resistance among pregnant women initiating ART in Uganda: a baseline evaluation of participants in the Option B+ clinical trial. [PDF]

Afr Health Sci, 2022
Amone A, Wavamunno P, Gabagaya G, Rukundo G, Namale-Matovu J, Malamba SS, Lubega I, Homsy J, King R, Nakabiito C, Nolan M, Fowler MG, Musoke P.   +12 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Early retention among pregnant women on 'Option B + ' in urban and rural Zimbabwe. [PDF]

AIDS Res Ther, 2021
Chimwaza AN, Tweya H, Mugurungi O, Mushavi A, Mukungunugwa S, Sithole N, Nyakura J, Senkoro M, Owiti P, Ncube R, Tapera T, Mandewo W, Edwards JK, Mangombe A, Taramusi I.   +14 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Probable perinatal depression and social support among women enrolled in Malawi's Option B+ Program: A longitudinal analysis. [PDF]

J Affect Disord, 2022
Bhushan NL, Stockton MA, Harrington BJ, DiPrete BL, Maliwichi M, Jumbe AN, Kulisewa K, Chagomerana MB, Pence BW, Gaynes BN, S4 Study Team, Hosseinipour MC.   +11 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

HIV Positive Pregnant Mothers' Perceptions and Experiences Regarding the Prevention of Mother-to-Child Transmission, Option B+ Program. [PDF]

J Patient Exp, 2021
Mbatha TL, Dube A.
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Preference-free option pricing with path-dependent volatility: A closed-form approach [PDF]

This paper shows how one can obtain a continuous-time preference-free option pricing model with a path-dependent volatility as the limit of a discrete-time GARCH model.
Steven L. Heston, Saikat Nandi
core  

Study of impact of WHO option B+ on maternal and perinatal outcome in HIV-positive women delivering at a tertiary care hospital, Delhi. [PDF]

Indian J Sex Transm Dis AIDS, 2022
Yadav R, Chopra K, Jaiswal N.
europepmc   +1 more source