Results 101 to 110 of about 5,024,521 (302)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Juridical-Legal Bases of Option Which Is Derived from Breakdown of the Contractual Obligation and Its Functions [PDF]
آموزههای فقه مدني, 2019 One of the issues that have been discussed in jurisprudential and legal books is the option which is resulted from the breakdown of the contract, which Iran’s civil code has also dealt with in the materials (441, 442, 443). In the meantime, the important
Ahmad Mortazi, مهدی صفرخانی
doaj
Choosing Your Nonmonotonic Logic: A Shopper’s Guide [PDF]
, 2018 The paper presents an exhaustive menu of nonmonotonic logics. The options are individuated in terms of the principles they reject. I locate, e.g., cumulative logics and relevance logics on this menu.
Hlobil, Ulf
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Australian Asian options [PDF]
We study European options on the ratio of the stock price to its average and viceversa. Some of these options are traded in the Australian Stock Exchange since 1992, thus we call them Australian Asian options.
Javier F. Navas, Manuel Moreno
core
Disabled Māori and disability support options [PDF]
, 2004 The goal of this research project was to provide information to enhance the development and implementation of an effective model of disability support service provision to Maori with disabilities.
Hickey, Huhana +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source