Results 211 to 220 of about 5,203,807 (351)

Angiotensin-converting enzyme inhibitors for ovarian cancer? — a new adjuvant option or a silent trap

, 2023
Katarzyna Regulska, Marcin Michalak, Tomasz Kolenda, Joanna Kozłowska-Masłoń, Kacper Guglas, Beata Stanisz   +5 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The nutritional environment and food access of female athletes at HBCUs: a qualitative analysis. [PDF]

Front Nutr
Uriegas NA, Winkelmann ZK, Emerson DM, Torres-McGehee TM.   +3 more
europepmc   +1 more source

Exploring standardized tests washback from the decolonial option: implications for rural teachers and students [PDF]

Yimmy Alexander Hoyos Pipicano
openalex   +1 more source

Combined Piled-Raft Foundation a Sustainable Option for Week Soil (Alluvial Soil)

, 2021
Devesh Ojha, Rajendra K. Srivastava
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Generating multiple-choice questions using reverse engineering techniques. [PDF]

Med Educ Online
Shin S, Choi J, Hong E, Lee M, Lee M.
europepmc   +1 more source

Comparison of two energy storage options for optimum balancing of wind farm power outputs [PDF]

, 2015
Barry Hayes, Alister Wilson, Roger Webster, Sasa Djokic   +3 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Correction: How to deal with the criterion of severe mental distress for late termination of pregnancy? A scoping literature review and a content analysis of clinical ethics consultations. [PDF]

BMC Med Ethics
Wetterauer C, Schürmann J, Winkler L, Westermair AL, Biller-Andorno N, Tschudin S, Manegold-Brauer G, Trachsel M.   +7 more
europepmc   +1 more source