Results 131 to 140 of about 58,764 (371)

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Optogenetics: Novel Tools for Controlling Mammalian Cell Functions with Light

International Journal of Photoenergy, 2014
In optogenetics, targeted illumination is used to control the functions of cells expressing exogenous light-activated proteins. Adoption of the optogenetic methods has expanded rapidly in recent years.
Toshihiro Kushibiki, Shinpei Okawa, Takeshi Hirasawa, Miya Ishihara   +3 more
doaj   +1 more source

Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration [PDF]

, 2016
Migratory immune cells use intracellular signaling networks to generate and orient spatially polarized responses to extracellular cues. The monomeric G protein Cdc42 is believed to play an important role in controlling the polarized responses, but it has
Gautam, N., Kalyanaraman, Vani, O\u27Neill, Patrick R   +2 more
core   +2 more sources

Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Neuroscience studies using optogenetics have greatly improved our understanding of brain circuits. Advances in the combined use of optogenetics and pharmacology to further probe important neurochemical signals has lagged, however, in large ...
Yi Zhang, Daniel C. Castro, Yuan Han, Yixin Wu, Hexia Guo, Zhengyan Weng, Yeguang Xue, Jokubas Ausra, Xueju Wang, Rui Li, Guangfu Wu, A. Vázquez-Guardado, Yiwen Xie, Zhaoqian Xie, Diana Ostojich, D. Peng, Rujie Sun, Binbin Wang, Yongjoon Yu, John P. Leshock, Subing Qu, C. Su, Wen Shen, T. Hang, Anthony R. Banks, Yonggang Huang, J. Radulovic, P. Gutruf, M. Bruchas, J. Rogers   +29 more
semanticscholar   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Neural reactivations during sleep determine network credit assignment. [PDF]

, 2017
A fundamental goal of motor learning is to establish the neural patterns that produce a desired behavioral outcome. It remains unclear how and when the nervous system solves this 'credit assignment' problem.
Bodepudi, Anitha, Ganguly, Karunesh, Gulati, Tanuj, Guo, Ling, Ramanathan, Dhakshin S   +4 more
core   +3 more sources

Implantable Light‐Powered Human Designer Cells for Electrical Energy Generation

Advanced Materials, EarlyView.
Inspired by the eel's electric organ, a miniature implantable biohybrid device is developed to generate electricity under light activation. The device utilizes a light‐dependent ion gradient formation that induced by genetically engineered human designer cells that express light‐sensitive membrane ion channels and proton pumps, working in synergy with ...
Shuai Xue, Zhihua Lin, Debasis Maity, Preetam Guha Ray, Mingqi Xie, Martin Fussenegger   +5 more
wiley   +1 more source

The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse

Neurobiology of Disease, 2014
The misfolding and aggregation of α-synuclein (aSyn) eventually lead to an accumulation of toxic forms that disturb normal neuronal function and result in cell death.
Mari H. Savolainen, Christopher T. Richie, Brandon K. Harvey, Pekka T. Männistö, Kathleen A. Maguire-Zeiss, Timo T. Myöhänen   +5 more
doaj   +1 more source

Chronically implantable LED arrays for behavioral optogenetics in primates

Nature Methods, 2020
Optogenetic methods have been widely used in rodent brains, but remain relatively under-developed for nonhuman primates such as rhesus macaques, an animal model with a large brain expressing sophisticated sensory, motor and cognitive behaviors.
R. Rajalingham, M. Sorenson, R. Azadi, Simon Bohn, James J. DiCarlo, Arash Afraz   +5 more
semanticscholar   +1 more source

Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials

Advanced Materials, EarlyView.
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker, Jara Saluena Martin, Annah‐Ololade Sangosanya, Anouk Verstuyft, Aurélie Van Wylick, Eveline Peeters   +5 more
wiley   +1 more source