Results 241 to 250 of about 55,224 (387)

Optogenetically induced sleep spindle rhythms alter sleep architectures in mice [PDF]

open access: bronze, 2012
Angela Kim   +6 more
openalex   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Entropic Repulsion and Local Order in Doubly Tethered Polymers on a Surface

open access: yesMacromolecular Theory and Simulations, EarlyView.
The study examines the behavior of mobile doubly tethered polymers on a 2D substrate. It analyzes conformational properties and end‐monomer ordering, considering the director between end‐monomers for local ordering. As tethering density increases, a transition from mushroom‐like to upright structures is observed.
Min Chu, Dieter W. Heermann
wiley   +1 more source

Development of optogenetics in the world and in Russia: leading researchers and technological drivers

open access: yesEkonomika Nauki, 2015
The article presents a scientometrical and patent analysis of a new perspective scientific area called «optogenetics» with the usage of bibliometric data bases Web of Science and Scopus, as well as other analytical tools such as Essential Science ...
A. V. Komarova   +2 more
doaj  

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

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