Results 301 to 310 of about 55,224 (387)
Towards the Development of Optogenetically-Controlled Skeletal Muscle Actuators [PDF]
Hyeonyu Kim, Devin Neal, H. Harry Asada
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Abstract Electroencephalography (EEG) has been instrumental in epilepsy research for the past century, both for basic and translational studies. Its contributions have advanced our understanding of epilepsy, shedding light on the pathophysiology and functional organization of epileptic networks, and the mechanisms underlying seizures.
Christos Panagiotis Lisgaras+14 more
wiley +1 more source
Cell type–specific genetic and optogenetic tools reveal hippocampal CA2 circuits
Keigo Kohara+11 more
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Abstract Objective Degeneration of hilar mossy cells in the dentate gyrus is an important hallmark of hippocampal sclerosis and is often observed in patients with temporal lobe epilepsy. To understand the pathogenesis of hippocampal sclerosis and develop novel neuroprotective treatments, it is critical to determine the mechanistic processes of mossy ...
Carolin Christina Koretz+5 more
wiley +1 more source
Monitoring and modulating cardiac bioelectricity: from Einthoven to end-user. [PDF]
De Coster T+5 more
europepmc +1 more source
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder+4 more
wiley +1 more source
Characterizing astrocyte-mediated neurovascular coupling by combining optogenetics and biophysical modeling. [PDF]
Suarez A, Fernandez L, Riera J.
europepmc +1 more source
Optogenetically‐induced sustained hypothalamic hyperexcitability impairs memory via thalamic spread
Abstract Objective Clinical investigators have hypothesized that interictal epileptiform discharges (IEDs) generated by hypothalamic hamartoma (HH) lead to cognitive dysfunction in patients with drug‐resistant gelastic seizures. Herein we provide causal evidence supporting this hypothesis by demonstrating that excitatory neural bursts, when propagating
Masaki Sonoda+11 more
wiley +1 more source