Results 301 to 310 of about 55,224 (387)

The role of electroencephalography in epilepsy research—From seizures to interictal activity and comorbidities

open access: yesEpilepsia, EarlyView.
Abstract Electroencephalography (EEG) has been instrumental in epilepsy research for the past century, both for basic and translational studies. Its contributions have advanced our understanding of epilepsy, shedding light on the pathophysiology and functional organization of epileptic networks, and the mechanisms underlying seizures.
Christos Panagiotis Lisgaras   +14 more
wiley   +1 more source

Cell type–specific genetic and optogenetic tools reveal hippocampal CA2 circuits

open access: green, 2013
Keigo Kohara   +11 more
openalex   +2 more sources

Chronic optogenetic stimulation of dentate gyrus granule cells in mouse organotypic slice cultures synaptically drives mossy cell degeneration

open access: yesEpilepsia, EarlyView.
Abstract Objective Degeneration of hilar mossy cells in the dentate gyrus is an important hallmark of hippocampal sclerosis and is often observed in patients with temporal lobe epilepsy. To understand the pathogenesis of hippocampal sclerosis and develop novel neuroprotective treatments, it is critical to determine the mechanistic processes of mossy ...
Carolin Christina Koretz   +5 more
wiley   +1 more source

Monitoring and modulating cardiac bioelectricity: from Einthoven to end-user. [PDF]

open access: yesEuropace
De Coster T   +5 more
europepmc   +1 more source

Closed-loop optogenetic intervention in mice

open access: green, 2013
Caren Armstrong   +3 more
openalex   +2 more sources

The cerebellum in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder   +4 more
wiley   +1 more source

Optogenetically‐induced sustained hypothalamic hyperexcitability impairs memory via thalamic spread

open access: yesEpilepsia, EarlyView.
Abstract Objective Clinical investigators have hypothesized that interictal epileptiform discharges (IEDs) generated by hypothalamic hamartoma (HH) lead to cognitive dysfunction in patients with drug‐resistant gelastic seizures. Herein we provide causal evidence supporting this hypothesis by demonstrating that excitatory neural bursts, when propagating
Masaki Sonoda   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy