Results 51 to 60 of about 1,578 (156)

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

AI-Driven Methane Emission Prediction in Rice Paddies: A Machine Learning and Explainability Framework

Methane
Rice cultivation accounts for roughly 10% of worldwide anthropogenic greenhouse gas emissions, making it a significant source of methane (CH4) Despite modest observational constraints, estimates of worldwide CH4 emissions from rice agriculture range from
Abira Sengupta, Fathima Nuzla Ismail, Shanika Amarasoma   +2 more
doaj   +1 more source

Efficient Hyperparameter Optimization for Reference Evapotranspiration Estimation with Limited Parameters: A Comparison of Optuna and Grid Search in the Doukkala Region, Morocco [PDF]

E3S Web of Conferences
Accurate estimation of reference evapotranspiration (ETo) is essential for irrigation scheduling and water resource management, particularly in semi-arid regions where meteorological data are often limited.
Belarbi Zaid, El Younoussi Yacine
doaj   +1 more source

Assessing Mesoscale Heterogeneities in Hard Carbon Electrodes Through Deep Learning‐Assisted FIB‐SEM Characterization, Manufacturing and Electrochemical Modeling

Advanced Energy Materials, EarlyView.
A combination of discrete and finite element method models for the current collector deformation and electrochemical performance analysis, respectively. The models are calibrated and validated with electrochemical and imaging data of hard carbon electrodes. These electrodes were manufactured with different parameters (slurry solid contents of 35 and 40
Soorya Saravanan, Imelda Cardenas‐Sierra, Pei Sun, Hari Raj, Daniele Duranti, Mahnoor Nafees, Edoardo Rossi, Marco Sebastiani, Paul Vigneaux, Martin Petit, Maxime Moreaud, Francisco Fernandez, Alejandro A. Franco   +12 more
wiley   +1 more source

Optimization of Scene and Material Parameters for the Generation of Synthetic Training Datasets for Machine Learning-Based Object Segmentation

Computers
Synthetic training data is often essential for neural-network-based segmentation when real datasets are difficult or impossible to obtain. Conventional synthetic data generation relies on manually selecting scene and material parameters. This can lead to
Malte Nagel, Kolja Hedrich, Nils Melchert, Lennart Hinz, Eduard Reithmeier   +4 more
doaj   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Enhanced meta ensemble stacking approach with XGBoost and optuna based detection of Parkinson's disease

Frontiers in Digital Health
Parkinson's disease (PD), a progressive neurological disorder affecting motor function, has been significantly rising in prevalence in recent years. Current diagnostic methods, relying on clinical observations, neurological exams, and periodical DaTscan ...
Annsley Mohan Joseph Raj, S. Lakshmi Kruthika, Abinaya S   +2 more
doaj   +1 more source

Overcoming the Nyquist Limit in Molecular Hyperspectral Imaging by Reinforcement Learning

Advanced Intelligent Discovery, EarlyView.
Explorative spectral acquisition guide automatically selects informative spectral bands to optimize downstream tasks, outperforming full‐spectrum acquisition. The selected hyperspectral data are used for tasks such as unmixing and segmentation. BandOptiNet encodes selection states and outputs optimal bands to guide spectral acquisition. Recent advances
Xiaobin Tang, Yongqing Zhang, Xinyu Deng, Hyeon Jeong Lee, Delong Zhang   +4 more
wiley   +1 more source

Estimating thermal radiation of vertical jet fires of hydrogen pipeline based on linear integral and machine learning

Scientific Reports
Accurate and efficient prediction of thermal radiant of hydrogen jet fire is important to schedule safety design and emergency rescue program for hydrogen pipelines. In response, this paper proposes a novel Optuna-improved back propagation neural network
Anqing Fu, Weidong Li, Mingxing Li, Hang Su, Chaoming Wang   +4 more
doaj   +1 more source