Results 261 to 270 of about 306,651 (371)

Reasoning‐optimised large language models reach near‐expert accuracy on board‐style orthopaedic exams: A multi‐model comparison on 702 multiple‐choice questions

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 2, Page 752-762, February 2026.
Abstract Purpose The purpose of this study was to compare the accuracy, calibration, reproducibility and operating cost of seven large language models (LLMs)—including four newer models capable of using advanced reasoning techniques to analyse complex medical information and generate accurate responses—on text‐only orthopaedic multiple‐choice questions
Pedro Diniz   +5 more
wiley   +1 more source

Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Increased miR‐3163 targets NUDT21, reducing CPSF5 levels and driving APA dysregulation. This results in 3′UTR shortening of CBFB, which stabilizes RUNX1 and promotes smooth muscle proliferation. PTGER3, is also shortened amplifying hypoxia‐induced RVSP. Together, these pathways contribute to vascular remodeling in PH. Image Created in https://BioRender.
Scott D. Collum   +17 more
wiley   +1 more source

p300 inhibition delays premature cellular senescence. [PDF]

open access: yesNPJ Aging
Di Fede E   +16 more
europepmc   +1 more source

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