Results 121 to 130 of about 86,733 (198)

Cis‐urocanic acid formation following far‐UVC exposure and associated signaling responses in keratinocytes

Photochemistry and Photobiology, EarlyView.
Far‐UVC (200–235 nm) has emerged as a safe and effective indoor disinfection tool, but effects on skin immunomodulation remain unclear. This study demonstrates that 222 nm far‐UVC converts trans‐urocanic acid (UCA) to its biologically active cis isomer at levels comparable with solar radiation. In keratinocytes, far‐UVC alone caused modest increases in
Lizzie Thomas, Gareth Hazell, Katarzyna Baczynska, Jinkang Zhang, Paul O'Mahoney   +4 more
wiley   +1 more source

Los orígenes de la fenomenología

, 1985
Interpretación de la obra de Daniel Herrera Restrepo, Los orígenes de la fenomenología, y su aporte al estudio de la filosofía en general y de la fenomenología en particular.
Díaz, Jorge Aurelio
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Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Orígenes-identificación. Una investigación en las edades de 9-12 años hasta...

, 1997
Trabajamos con un grupo de edad (9-12 años hasta 15 - 16 años) de ambos sexos, en el que consideramos que el proceso identificatorio, recibe determinaciones del medio socio-cultural.
Karothy, Rolando Hugo
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TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors

The Journal of Physiology, EarlyView.
Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck, Carlos Matellan, Cristina Bauset, Bella Raphael, Mary Nwaezeigwe, Emer Flynn, Kevin Okamoto, Desmond Winter, Colm Collins, Katie Doogan, Seán T. Martin, Glen Doherty, Seema S. Aceves, Mario C. Manresa   +13 more
wiley   +1 more source

Sinensetin Induces Oxidative Stress‐Mediated Apoptosis in Non‐Small Cell Lung Cancer Cells by Suppressing Nrf2/ARE‐Dependent Antioxidant Defense

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Sinensetin suppresses Nrf2/ARE signaling, increases intracellular ROS, and promotes mitochondrial apoptosis in A549 NSCLC cells. Partial rescue by NAC and Nrf2 overexpression supports a functional role for oxidative stress and Nrf2 suppression in the observed anticancer response.
Junyan Li, Ruoyun He, Jiake He, Jian Ye, Yu Xie, Binfan Yuan   +5 more
wiley   +1 more source

PRAME Augments K63‐Linked Ubiquitination and Stabilization of METTL3 to Promote Lung Adenocarcinoma Metastasis

MedComm, Volume 7, Issue 11, November 2026.
PRAME promotes lung adenocarcinoma metastasis by inducing K63‐linked ubiquitination of METTL3 at lysine 235, thereby enhancing METTL3 stability and m6A methyltransferase complex assembly. Elevated METTL3 activity increases m6A modification of TGFB2 mRNA, leading to activation of TGF‐β signaling and metastatic progression of lung adenocarcinoma (LUAD ...
Xia Yang, Xuemei Xu, Yaxuan Zhang, Jiamei Guo, Zhiyu Ye, Qiaorui Bai, Xiuqiao Yang, Shujun Liang, Xiang Dong, Xin Zhang, Jiyong Gu, Shuqin Dai, Hongchun Du, Meiwan Chen, Tianyu Tao, Hongyu Guan, Jueheng Wu, Han Tian, Junchao Cai, Mengfeng Li, Xu Li, Yi Yang   +21 more
wiley   +1 more source

Todorov e Orígenes

, 2019
O livro de Tzvetan Todorov Simbolismo e Interpretação formula dois modos de interpretar um texto, um que ele chama de “final,” e outro chamado “operacional.” Ele então escolhe a exegese patrística como modelo dessa leitura “final.” Este artigo se propõe ...
Gripp, Bruno Salviano
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FAM3A Inhibits Plasma Triglyceride Levels via Microvasculature‐Involved Enhancement of VLDL‐Triglyceride Hydrolysis and Lipid Uptake

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
FAM3A enhances the PPARα signaling, leading to upregulated expression of lipid transporters including CD36 and TCF15. The upregulated CD36 and TCF15 enhance FA uptake and trans‐endothelial delivery in MVECs. Meanwhile, FAM3A‐enhanced PPARα signaling also increases LPL expression in myocytes and LPL position in lumen side of microvasculature to promote ...
Xiaohong Song, Wenxuan Xiang, Xiangyu Xian, Lichai Yuan, Jianqiang Wu, Bintao Qiu, Dan Yang, Yuehong Zheng   +7 more
wiley   +1 more source

Los orígenes del orden político

, 2011
Reseña de Farrar, Straus and Giroux, Francis Fukuyama, Los orígenes del orden político, Nueva York, 2011, 585 pp., ISBN 978-0-374-22734-0.
Toledo Patiño, Alejandro
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