Results 141 to 150 of about 103,773 (262)

Rhaponticin Blocks Glycolysis‐Mediated Histone Lactylation to Suppress Tongue Squamous Cell Carcinoma via HIF‐1α Activity Inhibition

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu   +7 more
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang   +3 more
wiley   +1 more source

Office‐Based Pediatric Laryngospasm Simulation Case for OMS Residents

open access: yes
Journal of Dental Education, EarlyView.
Yuhyun Kim   +3 more
wiley   +1 more source

Maxillomandibular Advancement Outcomes in Obstructive Sleep Apnea by Age and Gender

open access: yesThe Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 36 studies (608 patients) found that maxillomandibular advancement significantly improves polysomnographic, cephalometric, and subjective measures of obstructive sleep apnea across both sexes and throughout the lifespan. Odds of surgical cure decline roughly 3% per year of age.
Matthew O. Herbst   +7 more
wiley   +1 more source

How I Do It: Nasoseptal Flap for Reconstruction of Isolated Soft Palate Defect

open access: yesThe Laryngoscope, EarlyView.
A vascularized nasoseptal flap (NSF) provides a novel transnasal option for repairing soft palatal fistulas when traditional transoral flaps have failed or are unavailable, potentially avoiding the morbidity of regional or free tissue transfer. In the current patient who had an 8 × 6 mm soft palatal fistula, the NSF was harvested from the septum and ...
Vincent M. Desiato   +3 more
wiley   +1 more source

Nasolabial Flap in Oncologic Oral Cavity Reconstruction: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
The nasolabial flap provides a reliable local reconstructive option for selected small‐ to oncologic oral cavity defects, with low flap‐related complications and minimal donor‐site morbidity. Outcomes should nevertheless be interpreted according to defect characteristics, flap design, and the predominantly retrospective nature of the available evidence.
Fabio Maglitto   +6 more
wiley   +1 more source

The Application of Telemedicine in Surgery

open access: yesMed Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang   +8 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Home - About - Disclaimer - Privacy