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Geriatric Elements and Oral Anticoagulant Prescribing in Older Atrial Fibrillation Patients: SAGE‐AF [PDF]

open access: bronzeJournal of The American Geriatrics Society, 2019
Oral anticoagulants are the cornerstone of stroke prevention in high‐risk patients with atrial fibrillation (AF). Geriatric elements, such as cognitive impairment and frailty, commonly occur in these patients and are often cited as reasons for not ...
Jane S. Saczynski   +15 more
openalex   +2 more sources

Safety of direct oral anticoagulants in patients with atrial fibrillation and high risk of stroke (review of literature) [PDF]

open access: diamondУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2020
Review discusses the problem of non-vitamin K antagonist oral anticoagulants safety in patients with non-valvular atrial fibrillation. Bleeding risk assessment while applying anticoagulant therapy, preventive methods for major bleeding (intracranial ...
E. I. Baranova   +4 more
doaj   +2 more sources

Nonoclusive thrombosis of mechanical mitral valve prosthesis caused by inadequate treatment of anticoagulant therapy resistance [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background. Oral anticoagulants have been used in the prevention of thromboembolic complications for over six decades. A rare, but possible problem in the application of these medications could be resistance to them. Case report.
Ivanović Branislava   +3 more
doaj   +3 more sources

Roles of oral anticoagulant use on the risk of 28-day mortality and in-hospital mortality in patients with acute respiratory distress syndrome [PDF]

open access: yesFrontiers in Pharmacology
AimThis study was to investigate the association between oral anticoagulant use and 28-day mortality and in-hospital mortality in patients with acute respiratory distress syndrome (ARDS).MethodsA total of 1754 ARDS patients were identified in database ...
Jiayang Huang   +5 more
doaj   +2 more sources

Artificial Intelligence–Enabled ECGs for Atrial Fibrillation Identification and Enhanced Oral Anticoagulant Adoption: A Pragmatic Randomized Clinical Trial [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atrial fibrillation (AF) is often underdiagnosed and undertreated by noncardiologists. This study evaluated whether artificial intelligence–enabled ECG (AI‐ECG) alerts could improve AF diagnosis and non–vitamin K antagonist oral anticoagulant ...
Wei‐Ting Liu   +15 more
doaj   +2 more sources

Evaluation of Direct Oral Anticoagulant Reversal Agents in Intracranial Hemorrhage

open access: yesJAMA Network Open, 2022
Key Points Question What outcomes are associated with direct oral anticoagulant (DOAC) reversal agents in intracranial hemorrhage (ICH)? Findings In a meta-analysis of 32 studies including 1832 patients with ICH, 4-factor prothrombin complex concentrate (
R. Chaudhary   +19 more
semanticscholar   +1 more source

Drug Interactions Affecting Oral Anticoagulant Use

open access: yesCirculation: Arrhythmia and Electrophysiology, 2022
Oral anticoagulants (OACs) are medications commonly used in patients with atrial fibrillation and other cardiovascular conditions. Both warfarin and direct oral anticoagulants are susceptible to drug-drug interactions (DDIs).
Philip L. Mar   +13 more
semanticscholar   +1 more source

Clinical Characteristics and Outcomes Associated With Oral Anticoagulant Use Among Patients Hospitalized With Intracerebral Hemorrhage

open access: yesJAMA Network Open, 2021
Key Points Question What is the association between prior oral anticoagulant use (factor Xa [FXa] inhibitors, warfarin, or none) and in-hospital outcomes among patients with nontraumatic intracerebral hemorrhage (ICH)?
Y. Xian   +11 more
semanticscholar   +1 more source

Availability of Specific Direct Oral Anticoagulant Reversal Agents in US Hospitals

open access: yesJAMA Network Open, 2021
This cross-sectional study assesses the availability of the direct oral anticoagulant reversal agents idarucizumab and andexanet alfa in US hospitals.
Zahir Kanjee, Marissa McCann, J. Freed
semanticscholar   +1 more source

Direct Oral Anticoagulant Use: A Practical Guide to Common Clinical Challenges

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Direct oral anticoagulants (DOACs) have quickly become attractive alternatives to the long‐standing standard of care in anticoagulation, vitamin K antagonist. DOACs are indicated for prevention and treatment of several cardiovascular conditions.
Ashley Chen, E. Stecker, Bruce A Warden
semanticscholar   +1 more source

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