Results 21 to 30 of about 2,024,265 (255)

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand, Förch, Christian, Lindhoff-Last, Edelgard, Mirceska, Ana, Pfeilschifter, Josef Martin (Prof. Dr.), Pfeilschifter, Waltraud, Steinmetz, Helmuth   +6 more
core   +6 more sources

Are patients on oral anticoagulation therapy aware of its effects? A cross-sectional study from Karachi, Pakistan

BMC Research Notes, 2020
Objective Oral anticoagulants are one of the most frequently used medications. However, these drugs have a range of side effects including potential life-threatening complications.
Ibrahim Zahid, Syed Wajih Ul Hassan, Nida Sehar Bhurya, Sheena Nadeem Alam, Choudhary Ahmed Hasan, Bakht Hussain Shah, Fasiha Bakhtawar Fatima, Ayesha Ahmed, Syed Sabih Ul Hassan, Javeria Hayat, Aqsa Zulfiqar, Rija Sheikh, Momin Aziz, Rabbia Siddiqi, Kaneez Fatima, Muhammad Shahzeb Khan   +15 more
doaj   +1 more source

Association of Ischemic Stroke, Major Bleeding, and Other Adverse Events With Warfarin Use vs Non–vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation With a History of Intracranial Hemorrhage

JAMA Network Open, 2020
This cohort study in Taiwan compares the clinical outcomes of warfarin use and non–vitamin K antagonist oral anticoagulant use in patients with atrial fibrillation with a history of intracranial hemorrhage using a nationwide cohort with atrial ...
Chuan-Tsai Tsai, J. Liao, C. Chiang, Yenn‐Jiang Lin, S. Chang, L. Lo, Yu-Feng Hu, Ta-Chuan Tuan, F. Chung, T. Chao, G. Lip, Shih‐Ann Chen   +11 more
semanticscholar   +1 more source

How we treat bleeding associated with direct oral anticoagulants [PDF]

, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +4 more
core   +1 more source

Outcomes Associated With Oral Anticoagulants Plus Antiplatelets in Patients With Newly Diagnosed Atrial Fibrillation. [PDF]

, 2020
Importance: Patients with nonvalvular atrial fibrillation at risk of stroke should receive oral anticoagulants (OAC). However, approximately 1 in 8 patients in the Global Anticoagulant Registry in the Field (GARFIELD-AF) registry are treated with ...
Bassand, J-P, Camm, AJ, Dabrowski, E, Fitzmaurice, DA, Fox, KAA, GARFIELD-AF Investigators, Gersh, BJ, Gibbs, L, Goldhaber, SZ, Goto, S, Haas, S, Kakkar, AK, Luo, K, Misselwitz, F, Pieper, KS, Turpie, AGG, Velentgas, P, Verheugt, FWA   +17 more
core   +2 more sources

Direct oral anticoagulant use and risk of severe COVID‐19

Journal of Internal Medicine, 2020
Hypercoagulability and thromboembolism are prominent features of severe COVID‐19, and ongoing anticoagulant use might be protective.
B. Flam, V. Wintzell, J. Ludvigsson, J. Mårtensson, B. Pasternak   +4 more
semanticscholar   +1 more source

Anticoagulants for acute ischaemic stroke [PDF]

, 2015
Peer reviewedPublisher ...
Counsell, Carl, Kane, Edward J, Sandercock, Peter A G   +2 more
core   +1 more source

Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant.

JAMA Internal Medicine, 2019
Importance Patients with atrial fibrillation (AF) who use a direct oral anticoagulant (DOAC) and request elective surgery or procedure present a common clinical situation yet perioperative management is uncertain. Objective To investigate the safety of
J. Douketis, A. Spyropoulos, J. Duncan, M. Carrier, G. Le Gal, A. Tafur, T. Vanassche, P. Verhamme, S. Shivakumar, P. Gross, Agnes Y. Y. Lee, E. Yeo, S. Solymoss, J. Kassis, G. Le Templier, S. Kowalski, M. Blostein, Vinay Shah, Elizabeth Mackay, Cynthia Wu, N. Clark, S. Bates, F. Spencer, E. Arnaoutoglou, M. Coppens, D. Arnold, J. Caprini, Na Li, K. Moffat, S. Syed, S. Schulman   +30 more
semanticscholar   +1 more source

Direct oral anticoagulant use in left ventricular thrombus

Thrombosis Journal, 2020
Left ventricular thrombus (LVT) is associated with a significant risk of ischemic stroke (IS) and peripheral embolization. Societal guidelines recommend the use of warfarin, with direct oral anticoagulants (DOACs) only for patients unable to tolerate ...
Z. Ali, Nicholas Isom, Tarun Dalia, Farhad Sami, Uzair Mahmood, Z. Shah, K. Gupta   +6 more
semanticscholar   +1 more source

Update on Extended Treatment for Venous Thromboembolism [PDF]

, 2018
The importance of assessing the probability of venous thromboembolism recurrence, a condition that includes deep vein thrombosis and pulmonary embolism, lies in the fact that it is the most important factor in deciding the duration of anticoagulant ...
Del Toro-Cervera, Jorge, Demelo-Rodríguez, Pablo, Llamazares-Mendo, Cristina, Marra, Alberto M, Peñaloza-Martínez, Eduardo, Proietti, Marco, Soria Fernández-Llamazares, Guillermo, Álvarez-Sala Walther, Luis   +7 more
core   +2 more sources