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Candida in oral pre-cancer and oral cancer

Medical Hypotheses, 2011
Oral pre-malignancies and carcinomas are common epithelial pathologies caused by a variety of etiological factors. In the oral cavity, candidiasis is the most frequent opportunistic fungal infection. Since the initial reports of an association between candidiasis with oral pre-cancer and cancer, various theories have been debated regarding the role of ...
Ramanjeneya Raju   +3 more
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The Oral Microbiome and Oral Cancer [PDF]

open access: possibleClinics in Laboratory Medicine, 2014
The role that bacteria play in the etiology and predisposition to cancer is of increasing interest, particularly since the development of high-throughput genetic-based assays. With this technology, it has become possible to comprehensively examine entire microbiomes as a functional entity.
Ian Ganly, Laura Y. Wang
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Cancer of the oral cavity

Current Problems in Surgery, 2000
Summary Treatment of SCCHN can have both acute and chronic sequelae and complications. Complications related to surgical treatment include injury to neurovascular structures and the thoracic duct, wound infection, and salivary fistulas. Radiotherapy injures the skin, mucosa, and parenchyma of the salivary glands of the oral cavity, which can lead to ...
Jeffrey N. Myers, Amy Y. Chen
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Notch signaling in oral pre-cancer and oral cancer

Medical Oncology, 2021
Notch signaling involves cell to cell contact. It is an ancient signaling mechanism that is conserved throughout the animal kingdom. The basic function of Notch signaling is to decide cell fate and execute asymmetrical division. Notch signaling is indispensable for embryo growth.
Kumud Nigam, Ratnesh Kumar Srivastav
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Oral Cancer

Mayo Clinic Proceedings, 2007
Five percent of all tumors occur in the head and neck, and approximately half of those occur specifically in the oral cavity. Of the 615,000 new cases of head and neck [corrected] tumors reported worldwide in 2000, 300,000 were primary oral cavity squamous cell carcinomas. Recent data from the Surveillance, Epidemiology, and End Results Program suggest
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Oral Cancer

Critical Reviews in Oral Biology & Medicine, 1990
In the U.S. oral cancer accounts for 2.1% of all cancers and 1% of cancer deaths. Two to three times as many males as females are affected. Blacks have more intra-oral cancer than whites, and their incidence and mortality rates have increased in recent years. The etiologic process very likely involves several factors.
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Alcohol and oral cancer

International Journal of Oral and Maxillofacial Surgery, 2005
Alcohol, particularly when associated with tobacco use, has been recognized as an important risk factor for mouth cancer for almost 50 years. Together, they are associated with approximately 75% of upper aerodigestive tract cancers. However, intake of alcohol remains high in many countries. The rising incidence of oral cancer has prompted a revaluation
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The pathology of oral cancer

Pathology, 2003
Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the disease at presentation.
George Boey   +2 more
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Oral Cancer Detection

Dental Clinics of North America, 2011
There are approximately 21,000 new cases of oral cancer every year. Although the oral cavity is relatively accessible to examination, malignant processes tend to present late with poor prognosis. To improve tumor outcome, early detection and treatment is essential.
Roger I. Grannum, Orville Palmer
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Oral cancers in India

Seminars in Oncology, 2001
Oral cancers in India constitute a major portion of all cancers. With a population of 1,000 million, this cancer poses many challenges. More than 90% of cases are tobacco-related, and hence eminently amenable to primary prevention. The progress made in these cancers is helping us to address the problem in a better way, bringing hope to overcome the ...
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