Results 131 to 140 of about 1,510,419 (253)

Oral candidiasis as a clinical marker of highly active antiretroviral treatment failure in HIV-infected patients

Infectio
Introduction: Oral candidiasis is an opportunistic infection that is readily detectable in the clinic. It has been used to assess the immune status of HIV patients as well as the effectiveness of highly active antiretroviral therapy.
Sandra Lopez-Verdin, Amalia Torrecilla-Ramirez, Ana Cristina Horta-Sandoval, Jaime Federico Andrade-Villanueva, Ronell Bologna-Molina   +4 more
doaj   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2261-2273, November 2026.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

Management of Patients with Oral Candidiasis

, 2015
Oral candidal infections are medically treated with antifungal agents. In the fungal cell membrane, steroid ergosterol is the target of the antifungals on the market, but similarity with the human cell membrane may cause host toxicity and unintended ...
Jesper Reibel, Kragelund, Camilla, Pedersen, Anne Marie Lynge, Reibel, Jesper, Camilla Kragelund, Anne Marie Lynge Pedersen   +5 more
core   +1 more source

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Current treatment of oral candidiasis: a literature review [PDF]

, 2014
Candidiasis or oral candidosis is one of the most common human opportunistic fungal infections of the oral cavity. This pathology has a wide variety of treatment which has been studied until these days. The present study offers a literature review on the
Garcia Cuesta, Carla, Sarrión Pérez, María Gracia, Bagán Sebastián, José Vicente   +2 more
core  

Real‐World Survival Outcomes of Venetoclax Combination Therapies in Acute Myeloid Leukemia: Impact of Minimal Residual Disease Status and Antifungal Prophylaxis

Hematological Oncology, Volume 44, Issue 6, November 2026.
ABSTRACT In recent years the addition of the oral BCL2 inhibitor venetoclax to hypomethylating agents (HMAs) has emerged as the standard‐of‐care for patients with acute myeloid leukemia (AML) who are not fit for intensive chemotherapy, significantly improving survival and quality‐of‐life.
Mariarita Sciumè, Alessandro Bosi, Alfredo Marchetti, Fabio Serpenti, Pasquale De Roberto, Sonia Fabris, Francesco Versino, Elena Tagliaferri, Francesco Passamonti, Nicola Stefano Fracchiolla   +9 more
wiley   +1 more source

Cutaneous and diphtheritic avipoxvirus infection confirmed by PCR in a great horned owl (Bubo virginianus) in Mexico

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A juvenile female great horned owl (Bubo virginianus) from Nuevo León, Mexico, presented with proliferative eyelid, beak, and pedal lesions, and yellow nodules on the hard palate. Histopathology revealed epidermal hyperplasia, ballooning degeneration and numerous eosinophilic intracytoplasmic inclusion bodies (Bollinger bodies), which are ...
Armando Trejo‐Chávez, Sibilina Cedillo‐Rosales, Karina Flores‐Martínez, Cecilia Ramírez‐Hernández, Ramiro Avalos‐Ramirez   +4 more
wiley   +1 more source

Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, Volume 53, Issue 11, Page 1000-1006, November 2026.
ABSTRACT Background Discoid lupus erythematosus (DLE) represents the most common variant of chronic cutaneous lupus erythematosus, a skin‐specific autoimmune disorder within the broader lupus erythematosus spectrum Clinically, DLE is characterized by erythematous, scaly plaques with areas of hyperpigmentation.
Ala' Abu‐Dayeh, Daniel Miller, Alessio Giubellino   +2 more
wiley   +1 more source

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

Immunology, Volume 179, Issue 3, Page 337-349, November 2026.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos, Vitor Marcel Faça, Eduardo Antonio Donadi, Ana Paula Masson, Carlos Crippa Coletto, Gustavo Ronconi Roza   +5 more
wiley   +1 more source

Oral Candidiasis: Manifestations, Treatment and Management in Immunocompromised Patients

 Oral candidiasis is a common condition in immunocompromised patients, such as those with HIV and diabetes. It manifests in acute forms, for example, pseudomembranous candidiasis and erythematous candidiasis, as well as in chronic forms, including ...
Lobbia, G., De Manzoni, R., Zangani, A., Faccioni, P., Colapinto, G., Ventorre, D., Melloni, F., Di Cosola, M., Montagna, P., Beccherle, M.   +9 more
core   +1 more source