Results 51 to 60 of about 1,983,411 (302)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Knowledge and risk perception of oral cavity and oropharyngeal cancer among non-medical university students

Journal of Otolaryngology - Head and Neck Surgery, 2016
Background To assess non-medical university students’ knowledge and perceived risk of developing oral cavity and oropharyngeal cancer. Methods A cross-sectional survey was conducted among non-medical students of a private Midwestern university in the ...
Nosayaba Osazuwa-Peters, Nhial T. Tutlam
doaj   +1 more source

Radical removal of advanced cancer of the oral cavity and oropharynx

Южно-Российский онкологический журнал, 2021
Surgery for advanced cancer of the oral cavity and oropharynx are among the most difficult. This is due to the topographical and anatomical features that limit the operating field and the proximity of the internal carotid artery, which penetrates into ...
P. V. Svetitskiy
doaj   +1 more source

15-Lipoxygenase-1 induced by interleukin-4 mediates apoptosis in oral cavity cancer cells

, 2006
It is unknown whether IL-4 induces apoptosis in oral cavity cancer (OCC) cells and, if so, what the mediator of this apoptosis is. Therefore, this study investigated whether apoptosis of OCC cells is induced by IL-4 and whether 15-lipoxygenase-1 (15-LO-1)
윤주헌, 김경수, 이정권
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Microbial Similarity and Preference for Specific Sites in Healthy Oral Cavity and Esophagus

Frontiers in Microbiology, 2018
Human microbial communities are highly complex ecosystems, but it remains unclear if microbial compositions have any similarity in distinct sites of the oral cavity and esophagus in particular.
Li Dong, Li Dong, Jian Yin, Jing Zhao, Shan-rui Ma, Hai-rui Wang, Meng Wang, Wen Chen, Wen-qiang Wei   +8 more
doaj   +1 more source

Effects of fibrin glue on wound healing in oral cavity

, 2003
Objectives. Healing after oral cavity surgery may be problematic in some cases, because it is a contaminated cavity. The purpose of this investigation was to evaluate the effect of fibrin glue on healing after surgical procedures in the oral ...
Oral, O, Yucel, EA, Olgac, V, Oral, CK
core   +1 more source

Oral HPV16 prevalence in oral potentially malignant disorders and oral cavity cancers

, 2020
The role of human papillomavirus type 16 (HPV16) in oral potentially malignant disorders (OPMD) and oral cavity carcinoma (OC) is still under debate.
Baeten, K, Kenny, L, Whitfield, BCS, Batstone, MD, Tang, KD, Frazer, IH, Walsh, LJ, Scheper, GC, Punyadeera, C, Menezes, L   +9 more
core   +1 more source

LIHNCS - Lugol's iodine in head and neck cancer surgery : a multicentre, randomised controlled trial assessing the effectiveness of Lugol’s iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma : study protocol for a randomised controlled trial [PDF]

, 2013
Background: Oral cavity and oropharynx cancer are increasing in incidence worldwide but survival outcomes have not significantly improved over the last three decades. The presence of dysplasia or carcinoma in situ at surgical margins following resection
McMahon, Jeremy, Mehanna, Hisham M., McConkey, Christopher C., Hisham Mehanna, Sutton, David N., Dunn, Janet, Cymerman, James A, McCaul, James A, Sutton, David N, Shaw, Richard, James A McCaul, Dunn, Janet A., McCaul, James A., Jeremy McMahon, David N Sutton, Cymerman, James A., Hislop, Stuart, McConkey, Chris, James A Cymerman, Stuart Hislop, Richard Shaw, Mehanna, Hisham; id_orcid, Chris McConkey, Janet Dunn   +23 more
core   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source