Results 91 to 100 of about 124,044 (216)

Impact of Infratemporal Fossa Clearance on Survival in Advanced Buccal Mucosa Cancers

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Buccal mucosa cancers are the most prevalent oral cavity cancers in South Asia, often attributed to widespread tobacco use. The current NCCN guidelines generally advise against primary surgery for locally very advanced (cT4b) buccal cancers involving the masticatory space and infratemporal fossa (ITF).
Sudhir Nair   +11 more
wiley   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili   +16 more
wiley   +1 more source

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah   +21 more
wiley   +1 more source

Toward a Typology of Patients With Head and Neck Cancer: Biopsychosocial Profiles Predicting Longitudinal Quality of Life

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Quality of life (QoL) in head and neck cancer (HNC) is influenced by complex biopsychosocial factors, yet few longitudinal studies have examined these relationships immediately post‐treatment. Methods In this prospective study, 232 patients newly diagnosed with primary HNC completed psychometric assessments, clinical interviews, and
Haley Deamond   +18 more
wiley   +1 more source

Management of Fungating Oral Cancer: A Case Report

open access: yesForum of Clinical Oncology
Fungating growths are most distressing causing substantial psychological distress for patients and families. Malodor associated with fungating growth causes social isolation, yet malodor management remains suboptimal.
Shunyu Neizekhotuo Brian   +3 more
doaj   +1 more source

Intraoperative Indocyanine Green Fluorescence Enables Primary Tumor Localization and Treatment De‐Escalation in SCCUP: A Case Report

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Unknown primary cancer in the head and neck presents a difficult surgical treatment dilemma. Patients with squamous cell carcinoma of unknown primary (SCCUP) typically present with an enlarging neck mass found on biopsy but with no indication of primary site on diagnostic exams such as flexible laryngoscopy, CT, MRI, and/or PET/CT ...
Nikhil Bellamkonda   +5 more
wiley   +1 more source

Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino   +3 more
wiley   +1 more source

Simultaneous Bi‐Jaw Reconstruction: Double Free Fibula Flap Following Resection of Synchronous Oral Malignancy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Simultaneous reconstruction of extensive maxillary and mandibular defects in oncological cases is a complex surgical challenge. Methods We report a case of a 56‐year‐old female with synchronous oral malignancy involving upper and lower alveolus.
Subhendu Khan   +3 more
wiley   +1 more source

Dental Rehabilitation of the Scapular Tip in Maxillary Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction The fibula‐free flap has traditionally been utilized to perform dental rehabilitation following maxillectomy. The purpose of this study is to present our experience with dental implantation of the scapula–tip‐free flap in midface reconstruction.
Leba M. Sarkis   +9 more
wiley   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik   +6 more
wiley   +1 more source

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