Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases
Advanced Science, EarlyView.Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu +9 more
wiley +1 more source
Retrospective Analysis: Postoperative CCRT Improved Treatment Outcome of Oral Cavity Cancer With Multiple Nodal Metastases but Without Extracapsular Spreading [PDF]
, 2012 Kang‐Hsing Fan +8 more
openalex +1 more source
Advanced Science, EarlyView.This work presents highly consistent GaN‐based thin‐film gas sensors prepared by MOCVD for non‐invasive breath analysis. The sensors exhibit tunable selectivity from oxidizing to reducing gases by incorporating In composition, ultra‐low detection limits and humidity resistance.
Yuxuan Wang +9 more
wiley +1 more source
Automatic Patient Modeling for Hyperthermia Treatment Planning of Head and Neck Cancer [PDF]
, 2015 Head and neck (H&N) cancer is the term used to describe a wide range of malig- nant tumors originating in the upper airways and swallowing tracts. In 2012, this disease accounted for approximately 5% of all cancers worldwide, with 680,000 new cases ...
Fortunati, V. (Valerio)
core +1 more source
Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment
Advanced Science, EarlyView.Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr. +20 more
wiley +1 more source
Advanced Science, EarlyView.The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
Advanced Science, EarlyView.This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source
Lip and Oral Cavity Cancer TNM Finding v7 [PDF]
, 2020 National Cancer Institute
openalex +1 more source
Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma [PDF]
, 2021 Elisabeth Pérez‐Ruiz +7 more
openalex +1 more source
The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information [PDF]
, 2010 The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information.
Baranova, Oxana V. +5 more
core +1 more source