Results 141 to 150 of about 223,172 (310)
Advanced Science, EarlyView.Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen +17 more
wiley +1 more source
Lip and Oral Cavity Cancer pM1 TNM Finding v6 and v7 [PDF]
, 2020 National Cancer Institute
openalex +1 more source
A theory for the tissue specificity of BRCA1/2 related and other hereditary cancers [PDF]
, 2010 Women who inherit a defective BRCA1 or BRCA2 gene have risks for breast and ovarian cancer that are so high and seem so selective that many mutation carriers choose to have prophylactic surgery. There has been much conjecture to explain such apparently
Bernard Friedenson
core +1 more source
Advanced Science, EarlyView.Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian +7 more
wiley +1 more source
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH DIAGNOSIS OF ORAL CAVITY CANCER
, 2021 Lara Isabella Souza Santos +6 more
openalex +2 more sources
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Objective The optimum duration of prophylactic antibiotics after pancreaticoduodenectomy following preoperative biliary drainage to prevent surgical site infections remains controversial. We evaluate whether a prolonged course of prophylactic antibiotics reduces surgical site infection after pancreaticoduodenectomy following biliary drainage ...
Kyohei Matsumoto +9 more
wiley +1 more source
Nationwide Survey of the Surgical Treatment for Hiatal Hernia in Japan
Annals of Gastroenterological Surgery, EarlyView.This nationwide study of 960 hiatal hernia surgeries in Japan found that patients with Type I hernia had distinct characteristics and more favorable surgical outcomes compared to Types II–IV. Postoperative dysphagia was significantly associated with Types II–IV, preoperative dysphagia, and esophageal strictures, highlighting the need for careful ...
Soji Ozawa +8 more
wiley +1 more source
Health EquityBackground: Oral cancer is one of the 10 most common cancers globally and represents a public health problem. Cultural practices and access to care are recognized as determinants of oral diseases, including cancer.
Cynthia Cantarutti +9 more
doaj +1 more source