Establishing a Quantitative Framework for Combined Oral Contraceptives: Evaluating the Impact of Drug-Drug Interactions on Exposure and Clinical (Surrogate) Efficacy Endpoints. [PDF]
Chun D +7 more
europepmc +1 more source
Abstract Objective A single oral dose of azithromycin (AZM) given during labor to women planning a vaginal delivery reduced maternal infections including sepsis, with a stronger effect in sub‐Saharan Africa than South Asia. Since maternal infection contributes to labor dysfunction and postpartum hemorrhage (PPH), we evaluated the effect of AZM on the ...
Larissa Sidze +37 more
wiley +1 more source
Evaluating the Impact of Oral Contraceptives on Pancreatic Cancer Risk: A Two-Sample Mendelian Randomization Analysis. [PDF]
Tang Y +7 more
europepmc +1 more source
Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake +4 more
wiley +1 more source
The effect of combined oral contraceptives on thrombin generation assessed on ST Genesia- a paired clinical study. [PDF]
Strandberg J +4 more
europepmc +1 more source
Abstract Objective Combined oral contraceptives (COCs) for dysmenorrhea management have been covered by the Japanese universal health insurance system since 2008. Several public awareness events regarding COC prescriptions for dysmenorrhea were implemented between 2013 and 2015, including media reports on COC‐related fatalities in 2013, drug safety ...
Risa Ishida +8 more
wiley +1 more source
Combined oral contraceptives alter ectonucleotidase and adenosine deaminase activities in peripheral blood cells. [PDF]
Moreschi BP +4 more
europepmc +1 more source
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley +1 more source
Predicting venous thromboembolism risk from endogenous thrombin potential-based normalized activated protein C sensitivity ratio assay: toward early assessment of combined oral contraceptives. [PDF]
Morimont L +4 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan +3 more
wiley +1 more source

