Results 141 to 150 of about 416,181 (265)

Peritoneal dialysis-related peritonitis caused by <i>Mycobacterium brisbanense</i>: A case report and literature review. [PDF]

IDCases
Hasegawa T, Ono D, Kawamura T, Ryo Y, Komori K, Yamaguchi T, Maeshima A, Mimura K, Tsukada K, Oka H.   +9 more
europepmc   +1 more source

Oral Tradition as Cultural Pedagogy

JURNAL PENELITIAN KEISLAMAN
The Kotah Pehapeng–Waha Pledang oral tradition of Lamakera, East Flores, represents an intangible cultural heritage that embodies educational, moral, spiritual, and collective identity values. This study adopts a qualitative approach using literature review and a phenomenological-hermeneutic paradigm.
openaire   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Rezafungin and catheter-related candidemia: a new player in a high-stakes game. [PDF]

Infez Med
Venturini S, Reffo I, Zanus-Fortes A, Del Fabro G, Callegari A, Giovagnorio F, Negri C, Casarotto M, Basaglia G, Zanusso C, Basso B.   +10 more
europepmc   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Acute and sub-chronic oral toxicity evaluation and gut microbiota modulation of indigenous <i>Lactobacillus helveticus</i> strains from Indonesia in rats. [PDF]

Toxicol Rep
Kristiana H, Kartawijaya M, Tuentifiany L, Hartanti AW, Tjandrawinata RR.   +4 more
europepmc   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Community-onset symptomatic urinary tract infections (SUTI) caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales: independent predictors and comparative effectiveness of oral agents. [PDF]

Antimicrob Steward Healthc Epidemiol
Zilberman-Itskovich S, Masarwi M, Levy E, Iflah M, Levi Steinweg I, Yapryntsev N, Mednyk S, Gur-Lavy R, Alfahel S, Amity K, Itzhaki A, Marchaim D.   +11 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

<i>Streptococcus Pyogenes</i> and Acute Rheumatic Fever: How Strong are the Links in the Chain? [PDF]

Glob Heart
Wirth SH, Beaton AZ, Steer A.
europepmc   +1 more source