Results 191 to 200 of about 403,449 (247)

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

open access: yesAdvanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang   +9 more
wiley   +1 more source

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

open access: yesAdvanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi   +12 more
wiley   +1 more source

Case Series: Use of Dalbavancin for Invasive Gram-Positive Infection in Children. [PDF]

open access: yesJ Pediatr Pharmacol Ther
Chang AJ   +10 more
europepmc   +1 more source

From Needle to Sachet: Fosfomycin Versus Amikacin for Cystoscopy Prophylaxis. [PDF]

open access: yesCureus
Quadir U   +9 more
europepmc   +1 more source

Identification of GLDN<sup>+</sup> odontogenic stem cells as crucial for human tooth development and regeneration. [PDF]

open access: yesInt J Oral Sci
Liao C   +11 more
europepmc   +1 more source

Therapeutic Tools for Vulvovaginal Candidiasis: Current and Emerging Antifungal Agents. [PDF]

open access: yesJ Fungi (Basel)
Quindós G   +6 more
europepmc   +1 more source

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