Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms. [PDF]
Superparamagnetic iron oxide nanoparticles (SPIONs) generate heat upon exposure to an alternating magnetic field (AMF), which has been studied for hyperthermia treatment and triggered drug release.
Ansari SR +6 more
europepmc +5 more sources
Rational prescribing and dispensing of oral dosage forms of medicines to children: an observational study [PDF]
Introduction Irrational prescribing and dispensing of oral dosage forms of medicines to paediatric patients are major public health issues, especially in low-income and middle-income countries. Many challenges affect the rational use of oral dosage forms
Ashenafi Kibret Sendekie +6 more
doaj +3 more sources
The Past, Present, and Future of Oral Dosage Forms for Children. [PDF]
The administration of medications to children has been a challenge for parents and caregivers for generations. Pharmaceutical companies have often overcome the difficulties of weight-based dosing and the -inability of most young children to swallow solid
Meyers RS.
europepmc +2 more sources
Selective Laser Sintering of Solid Oral Dosage Forms with Copovidone and Paracetamol Using a CO2 Laser. [PDF]
Material suitability needs to be considered for the 3D printing of solid oral dosage forms (SODFs). This work aims to assess the suitability of a CO2 laser (λ = 10.6 μm) for selective laser sintering of SODFs containing copovidone and paracetamol. First,
Gueche YA +6 more
europepmc +2 more sources
Rational Dispensing of Oral Dosage Forms of Medicines to Children and Its Associated Factors in South West Ethiopia [PDF]
Fikadu Ejeta, Diriba Feyisa, Temesgen Aferu, Jafer Siraj, Demeke Melkam, Ahmed Ali School of Pharmacy, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Aman, EthiopiaCorrespondence: Fikadu Ejeta, Tel +251910136034, Email fikaduejeta ...
Ejeta F +5 more
doaj +2 more sources
3D printing of solid oral dosage forms: numerous challenges with unique opportunities. [PDF]
Since the FDA approval of Spritam, there has been a growing interest in the application of 3D printing in pharmaceutical science. 3D printing is a method of manufacturing involving the layer-by-layer deposition of materials to create a final product ...
Ogochukwu Lilian Okafor-Muo +3 more
semanticscholar +2 more sources
Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Meloxicam [PDF]
This monograph evaluates the scientific and regulatory underpinnings for bioequivalence (BE) waiver of immediate-release (IR) solid oral meloxicam formulations, as a surrogate for in vivo pharmacokinetic trials.
Aixin Guan +5 more
doaj +2 more sources
Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms [PDF]
The aim of this study is to investigate the influence of polymer chemistry on the properties of oral dosage forms produced using selective laser sintering (SLS).
Tikhomirov Evgenii +7 more
doaj +2 more sources
The Role of Functional Excipients in Solid Oral Dosage Forms to Overcome Poor Drug Dissolution and Bioavailability. [PDF]
Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract.
van der Merwe J +3 more
europepmc +2 more sources
Oral drug products have become indispensable in modern medicine because of their exceptional patient compliance. However, poor bioavailability of ubiquitous low‐water‐soluble active pharmaceutical ingredients (APIs) and lack of efficient oral drug ...
Patrick S Doyle, Liang-Hsun Chen
exaly +2 more sources

