Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
Advanced Science, EarlyView.This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li +8 more
wiley +1 more source
Mechanism of Ciclosporin-induced gingival hyperplasia An in vitro study of the effect of ciclosporin on human gingival fibroblasts and oral keratinocytes [PDF]
, 2011 PhDObjectives: Ciclosporin (CsA) is a potent and effective immuno-suppressive drug, but its use is associated with the development of gingival hyperplasia in up to 70% of patients.
Hanino, Mohammad
core
Advanced Science, EarlyView.Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu +4 more
wiley +1 more source
Advanced Science, EarlyView.MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang +7 more
wiley +1 more source
Expression and function of resolvin RvD1n-3 DPA receptors in oral epithelial cells. [PDF]
Eur J Oral Sci, 2022 Balta MG +9 more
europepmc +1 more source
Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery
Advanced Science, EarlyView.Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie +11 more
wiley +1 more source
The effects of smoking on genotoxic and histopathologic damage in exfoliated oral epithelial cells and the periodontium: A cross-sectional study. [PDF]
Medicine (Baltimore), 2023 Alkan B, Koroglu-Aydin P.
europepmc +1 more source
Advanced Science, EarlyView.Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang +12 more
wiley +1 more source
Development of an in vitro model for investigating the properties of human prostate epithelial cells and prostatic carcinoma cells [PDF]
, 2009 Prostate cell lines were derived from two regions of prostate tissue from the same patient. The objective was to produce cell lines (as a useful in vitro model) from these two different regions which exhibit different properties for carcinoma development.
Weaver, Jennifer
core
The Anti-Inflammatory Effects of Iberin on TNF-α-Stimulated Human Oral Epithelial Cells: In Vitro Research. [PDF]
Biomedicines, 2022 Hosokawa Y +7 more
europepmc +1 more source