Results 91 to 100 of about 1,874,724 (233)

From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems

open access: yesChemistry – A European Journal, EarlyView.
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui   +5 more
wiley   +1 more source

Community Head and Neck Cancer Knowledge, Engagement, Research, and Screening (CHECKERS): Protocol for a Community‐Engaged Approach to Head and Neck Cancer Prevention

open access: yesCancer Nexus, EarlyView.
ABSTRACT Introduction Unequal access to care is associated with disparities in prevention, early detection, and outcomes of head and neck cancer (HNC), especially in underserved populations. Community‐engaged research (CEnR) aims to build capacity for community members to address health inequity via bidirectional partnerships with healthcare ...
Nicholas A. Frisco   +11 more
wiley   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz   +5 more
wiley   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

open access: yesClinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila   +5 more
wiley   +1 more source

Protecting All Children's Teeth (PACT): Oral Habits

open access: yesMedEdPORTAL, 2014
Protecting All Children's Teeth (PACT) was created by the AAP Oral Health Initiative to educate medical students, residents, pediatric primary care providers, and others interested in infant, child, and adolescent health about the importance of oral ...
Melinda Clark, David Krol
doaj   +1 more source

Dental development in the tropical gar (Atractosteus tropicus) and the evolution of vertebrate dentitions

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova   +4 more
wiley   +1 more source

Prevalence and Etiological Distribution of Midline Diastema- An Institutional Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Introduction: The space between two central incisors is called diastema. It is aesthetically very unpleasant to the patients. Besides, this it may be a sign of underlying pathology. So proper research about diastema is necessary.
Sutanu Modak   +5 more
doaj   +1 more source

Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 912-922, April 2025.
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi   +9 more
wiley   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

open access: yesEpileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron   +6 more
wiley   +1 more source

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