Results 241 to 250 of about 182,622,249 (336)

Stress and resilience during pregnancy: relationship with perceived oral health and oral health related quality of life. [PDF]

BMC Oral Health
Nazir MA, Ahmed SF, Alramadhan R, Aldarurah B, Abdullah L, Albrahim R, Al-Ansari A.   +6 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Oral Health-Related Quality of Life and Its Determinants in Children and Adolescents with Autism Spectrum Disorder: A Scoping Review. [PDF]

Dent J (Basel)
Murariu A, Bobu L, Iovan G, Gelețu GL, Leon LI, Teodorescu AC, Zapodeanu D, Onofrei BA, Frățilă DN, Lupu CI, Baciu ER.   +10 more
europepmc   +1 more source

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

Advanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu, Chenguang Liu, Weihong Zheng, Xiaofei Tong, Zhengwei Gui, Zonghong Lu, Sun Ieong, Lin Zhang   +7 more
wiley   +1 more source

Association of clinical consequences of untreated caries in early childhood with oral health-related quality of life. [PDF]

Rev Bras Epidemiol
Silva RCDD, Campioni FLDS, Guerra HS, Meller FO, Quadra CA, Camargo Júnior EB, Schäfer AA.   +6 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Oral health related quality of life and dental caries of adults in Ebolowa, Cameroon: a cross sectional study. [PDF]

BMC Oral Health
Chimi N, Ebogo M, Mboua V, Agoons B, Eng YC, Zing S, Kwedi K, Nkolo F, Eya E, Bombah F, Bengondo C.   +10 more
europepmc   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Oral Health Literacy and Oral Health-Related Quality of Life Among Peruvian Children. [PDF]

Rev Cient Odontol (Lima)
Casapaico-Cucche C, Evaristo-Chiyong T, Luza-Montero S.   +2 more
europepmc   +1 more source