Results 91 to 100 of about 10,780,138 (382)

Dental Therapy of Patients Prior to Endoprostheses: A Retrospective, Telephone-Based Cohort Study

open access: yesDentistry Journal, 2023
The aim of this study was to assess, whether patients prior to endoprosthesis (EP) visit their dentist for need-oriented therapy and whether this would be associated with the occurrence of complications.
Gerhard Schmalz   +5 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Prevalence of Oral Pain and Barriers to use of Emergency Oral Care Facilities Among Adult Tanzanians. [PDF]

open access: yes, 2008
Oral pain has been the major cause of the attendances in the dental clinics in Tanzania. Some patients postpone seeing the dentist for as long as two to five days.
Ahadieli Raphael Senkoro   +24 more
core   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

DENTURE BASES -VEHICLE FOR ORAL HEALTH MEDICATION

open access: yesRomanian Journal of Medical and Dental Education, 2020
Introduction. The rapidly increasing aging population of developed countries is expected to escalate the demand for prosthodontic treatment, especially that of removable dentures, which remains the most common treatment option for elderly, edentulous ...
Dana Gabriela Budală   +5 more
doaj  

64180 The Proportion of Young Patients with Acute Surgical Pain and Development of Opiate Abuse Disorders

open access: yesJournal of Clinical and Translational Science, 2021
IMPACT: The importance of this study is to evaluate the responses following the exposure of opioid drugs in young adults to address the current opioid epidemics OBJECTIVES/GOALS: To compare the proportion of patients between 18 and 25 years of age, who ...
Armando Uribe-Rivera   +5 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

THE TWOFOLD PERSPECTIVE OF SCHOOLCHILDREN’S ORAL HEALTH

open access: yesRomanian Journal of Oral Rehabilitation
Aim of the study: This study identifies the optimal condition for the efficient integration of prevention in schools, as well as the actors who contribute to achieving this.
Anca-Cristina Perpelea   +6 more
doaj   +1 more source

Association of oral health literacy with oral health behavior and oral health outcomes among adult dental patients

open access: yesIndian Journal of Dental Research, 2020
Aims: To evaluate the association of oral health literacy (OHL) with oral health behavior and oral health outcomes among dental patients in Hyderabad City. Settings and Design: Cross-sectional study among dental patients.
Jagadeeswara Rao Sukhabogi   +3 more
doaj   +1 more source

A clinical and radiographic study of implants placed in autogenous bone grafts covered by either a platelet-rich fibrin membrane or deproteinised bovine bone mineral and a collagen membrane: a pilot randomised controlled clinical trial with a 2-year follow-up

open access: yesInternational Journal of Implant Dentistry, 2021
Purpose To compare the survival and clinical performance of implants placed in sites previously augmented with autogenous bone grafts covered by either a platelet-rich fibrin (PRF) membrane (PRF group) or a standard procedure (gold standard) involving ...
Jens Hartlev   +3 more
doaj   +1 more source

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