Results 61 to 70 of about 2,768,375 (310)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Significance of oral health education in maintaining oral health

open access: yesOrapuh Journal, 2021
This article is a qualitative review of the variables that are significant to maintaining oral health through oral health education. The consequences of lack of oral health awareness were also addressed by reviewing the story of a village girl with poor ...
Johnson John Omale   +5 more
doaj  

Public health and dental caries in young children in deprived communities in Scotland [PDF]

open access: yes, 2012
Dental  caries  is  the  most  prevalent  disease  worldwide,  and  is  caused  by  a  complex  interaction of tooth susceptibility, nutrition and the oral environment.  In young children it  can have a major impact on their quality of life, and is the 
Chambers, Stephanie
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An Assessment of Dentists' Oral Health

open access: yesJournal of Islamic International Medical College, 2015
Objective: The aim of the study was to access the oral health maintenance behavior patterns among dentists. Study Design: Questionnaire based cross sectional study.
Muhammad Humza Bin Saeed, Anum Zehra Khan, Nageen Akhtar, Sundas Tanveer, Sumayya Mehbub, Rabbia Sana, Alina Qureshi
doaj  

Oral health knowledge, attitudes, and behaviors of adult patients attending a dental school hospital in Egypt: a cross-sectional study

open access: yesScientific Reports
Oral health is a significant contributor to public health and a basic determinant of general health. As Egypt shows high prevalence of oral diseases, the aim of this study is to assess the oral health knowledge, attitudes and behaviors (KAB) among ...
Mennatollah Nagy Sharkawy, Omar Shaalan
doaj   +1 more source

Probiotic Biotherapy: Discussing its Influential Role in Oral Health [PDF]

open access: yes, 2020
Introduction: Probiotics are widely known for their health promoting benefits, especially with its association to gastrointestinal health. For many years, most research has been focused on the prevention or treatment of gastrointestinal infections or ...
Florez, Karla, Sullano, Claudette
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Oral Health Practices, Beliefs and Dental Service Utilization of Albanian Immigrants in Milwaukee, Wisconsin: A Pilot Study [PDF]

open access: yes, 2018
There is limited information on the oral health of Albanian immigrant population residing in the U.S. This creates a hinderance to developing and implementing appropriate dental care programs for the population.
Okunseri, Christopher   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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