Results 91 to 100 of about 1,683,140 (320)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Factors associated with oral health care behavior of people with type 2 diabetes mellitus: A hospital-based, cross-sectional study.

PLoS ONE
BackgroundOral healthcare behavior determines oral health status and the incidence of oral diseases. People with type 2 diabetes mellitus (T2DM) are at-risk of having low oral healthcare behavior and disease-related oral health.ObjectiveTo investigate ...
Kamonchanok Sairat, Nitikorn Phoosuwan
doaj   +1 more source

Caregivers' oral health knowledge, attitude and behavior toward their children with disabilities

Journal of Dental Sciences, 2017
Background/purpose: This study was undertaken to document the knowledge, attitude and behavior among family caregivers, and to identify the related factors influencing their behavior in promoting their and children's oral health. Materials and methods: A
Hsiu-Yueh Liu, Jung-Ren Chen, Szu-Yu Hsiao, Shun-Te Huang   +3 more
doaj   +1 more source

Socioeconomic inequality in oral health behavior in Iranian children and adolescents by the Oaxaca-Blinder decomposition method: the CASPIAN- IV study

International Journal for Equity in Health, 2016
BackgroundThe present study set to describe the socioeconomic inequality associated with oral hygiene behavior among Iranian pediatric population.MethodsA representative sample of 13486 school students aged 6–18 years was selected through multistage ...
S. Safiri, R. Kelishadi, R. Heshmat, A. Rahimi, S. Djalalinia, Anoosheh Ghasemian, A. Sheidaei, M. Motlagh, G. Ardalan, M. Mansourian, H. Asayesh, M. Sepidarkish, M. Qorbani   +12 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

An epidemiological investigation of the oral health behavior of 7 680 adolescents aged 12-15 years in Guangdong Province

口腔疾病防治, 2020
Objective To investigate the oral health behavior of urban and rural students in the 12~15 year age group in Guangdong Province, aiming to provide informational support for adolescent oral health care. Methods A multistage stratified sampling method with
SHANG Linjuan, ZHANG Jianming, LI Jiankai, LI Jianbo, HUANG Shaohong   +4 more
doaj   +1 more source

Preconception Oral Health Is Associated with Modifiable Health Behaviors

Journal of Dental Research
The health of prospective parents before conception (i.e., preconception health) has important intergenerational consequences. Although oral health is associated with several reproductive outcomes, it is often absent from preconception health promotion.
J.C. Bond, M.A. Simancas-Pallares, K. Divaris, R.I. Garcia, M.P. Fox, L.A. Wise, B. Heaton   +6 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Romantic and sexual behavior in young adolescents : repeated surveys in a population-based cohort [PDF]

, 2010
Adverse outcomes of teenage sexual activity are common in the United Kingdom. We used a computer-assisted interview to ask young adolescents aged 11-12 years (N = 6856) and 12 -13 years (N = 6801) who were part of the Avon Longitudinal Study of Parents ...
Andrea E. Waylen, Andrew Ness, Cotton, S., Dieter Wolke, Health Behaviour in School-Aged Children Study., Nicola Low, Phil McGovern   +6 more
core   +1 more source