Results 51 to 60 of about 1,144,489 (307)

Conservative management of Oral Submucous Fibrosis in early and intermediate stage

Journal of Oral Biology and Craniofacial Research, 2018
Aims & objective: To evaluate the efficacy of combined intralesional injection of Hyaloronidase and Triamcinolone with third molar removal in early and intermediate stage (Stage II & III) of Oral Submucous Fibrosis (OSMF) for improvement in mouth
Sachin Rai, Vidya Rattan, Akshat Gupta, Praveen Kumar   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Need for oral health awareness among students in Nigeria

Orapuh Journal, 2020
Oral health refers to a state of not having chronic orofacial pain, oral and throat cancers, or birth defects, oral infections and ulcers, periodontal disease, tooth loss, and other disorders that affect the oral cavity. Oral health awareness remains an
Francis C. Nweke, VE ADAMU, Ndidiamaka Ijeoma Eneojo   +2 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Impact of School Based Oral Health Education Programmes in India: A Systematic Review [PDF]

Journal of Clinical and Diagnostic Research, 2013
The teaching of Oral Health Education aims at preventing the dental disease and promoting dental health at early stages. Schools are powerful places to shape the health, education and well-being of our children.
Ramandeep Singh Gambhir, Ramandeep Kaur Sohi, Tarun Nanda, Gurjashan Singh Sawhney, Saniya Setia   +4 more
doaj   +1 more source

Demographics, social position, dental status and oral health-related quality of life in community-dwelling older adults [PDF]

, 2015
PURPOSE: To identify demographic, socioeconomic and dental clinical predictors of oral health-related quality of life (OHRQoL) in elderly people. METHODS: Cross-sectional study involving 613 elderly people aged 65–74 years in Manaus, Brazil.
Cardoso, Evangeline Maria, Rebelo, Maria Augusta Bessa, Robinson, Peter G, Vettore, Mario Vianna   +3 more
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Effectiveness of oral health education on 8- to 10-year-old school children in rural areas of the Magway Region, Myanmar

BMC Oral Health, 2021
Background Oral diseases are common and widespread around the world. The most common oral diseases are preventable, and early onset is reversible. Myanmar faces many challenges in rendering oral health services, because approximately 70% of the total ...
Kyu Kyu Swe, Aung Kyaw Soe, Saw Htun Aung, Htin Zaw Soe   +3 more
doaj   +1 more source

Parental Perceptions of Oral Health and School-Based Dental Sealant Programs [PDF]

, 2016
Introduction: Community Health Needs Assessment (University of Vermont Medical Center, 2013) Identified oral health in pediatric population as a primary concern Barriers to dental care cited: access, affordability, education School-Based Sealant Program (
Cole, Julie, Davis, Wendy, Donnelly, Laura, Evans, Peter, Fontaine, Kristin, Grant, Ian, Imeda, Allicia, Kula, Daniel, Park, Clare, Wu, Hao Fang   +9 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source