Results 211 to 220 of about 7,690,612 (280)

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

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Oral history

Qualitative Research Methods for Media Studies, 2021
Omgang met de eigentijdse geschiedenis is ondenkbaar zonder verhalen over het verleden. Selma Leydesdorff heeft jarenlang nationaal en internationaal een centrale rol gespeeld in de ontwikkeling van oral history, een vakgebied dat in de wetenschappelijke praktijk van het historisch onderzoek in de afgelopen decennia is uitgegroeid tot een ...
Bonnie S. Brennen
semanticscholar   +5 more sources

Oral History

2023
Seit gut vierzig Jahren bereichert die Oral History die geschichtstheoretischen und methodischen Debatten der deutschsprachigen Zeitgeschichte. Zwar ist die anfängliche Skepsis gegenüber der Oral History längst einer breiten Akzeptanz und (teils unreflektierten) Anwendung gewichen.
Andrea, Althaus, Linde, Apel
openaire   +2 more sources

History, Memory, and Identity: Oral History in China

Oral History Review, 2020
Oral history has attracted steadily increasing scholarly and public attention in China during the past two decades. This article surveys the landscape of oral history in China and addresses two core questions: first, why has oral history become popular ...
Na Li
semanticscholar   +1 more source

The Challenge of Oral History to Environmental History

, 2020
Oral history has much to offer environmental history, yet the possibilities and promises of oral history remain underutilised in environmental history and environmental studies more broadly.
B. Williams, M. Riley
semanticscholar   +1 more source

Oral history

The Routledge Handbook of Global Historical Archaeology, 2020
K. Massheder-Rigby
semanticscholar   +3 more sources

Rethinking Oral History and Tradition

, 2019
For many indigenous peoples, oral history is a living intergenerational phenomenon that is crucial to the transmission of our languages, cultural knowledge, politics, and identities.
Nēpia Mahuika
semanticscholar   +1 more source