Results 191 to 200 of about 2,294,107 (307)

Diagnostic challenges and clinical management gaps in HPV-related oral lesions. [PDF]

open access: yesFront Oral Health
Anaya-Saavedra G   +2 more
europepmc   +1 more source

Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

open access: yesAdvanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou   +7 more
wiley   +1 more source

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

open access: yesAdvanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang   +14 more
wiley   +1 more source

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

open access: yesAdvanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang   +9 more
wiley   +1 more source

Oral soft tissue lesions: A guide to differential diagnosis Part II: Surface alterations

open access: yes
able etiology and significance; their appropriate management relies on their accurate diagnosis. Considerable overlapping of the signs and symptoms produced by these diverse conditions poses significant problems for their diagnosis, which can be resolved
Nikitakis, Nikolaos G.
core  

Accuracy of AI Tools in the Diagnosis of Benign, Potentially Malignant and Malignant Oral Lesions: A Pilot Study. [PDF]

open access: yesJ Clin Med
Monteiro L   +12 more
europepmc   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

open access: yesAdvanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong   +9 more
wiley   +1 more source

Specific (granulomatous) oral lesions of sarcoidosis: Report of two cases

open access: yes
Sarcoidosis is a multisystemic granulomatous disease of unknown etiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions.
Marcoval Caus, Joaquim   +1 more
core  

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