Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla +8 more
wiley +1 more source
Oral lichen planus: an overview
Lichen planus (LP) is a chronic inflammatory muco-cutaneous disease. Since disorders of NK-cell functional activity could be observed in patients with LP, it is considered to be an autoimmune disease. The pathogenesis of LP is complex and not completely understood.
openaire +2 more sources
Distinct Immunological Features Compared to Lichen Planus and Oral Lichen Planus [PDF]
Dong Min Lim,1 DoYeon Kim,2 Hye-Min Ju,3,4 Sung-Hee Jeong,3,4 Yun Hak Kim,5– 7 Soo-Min Ok,3,4 Hae Ryoun Park2,5,8 1Interdisciplinary Program of Genomic Data Science, Pusan National University, Yangsan, 50612, Republic of Korea; 2Department of Oral ...
Park HR +6 more
core
Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations
Several therapeutic agents have been investigated for the treatment of oral lichen planus (OLP). Among these are corticosteroids, retinoids, cyclosporine, and phototherapy, in addition to other treatment modalities. A systematic review of clinical trials
A. Migliorati, Cesar +19 more
core +2 more sources
Disease scoring systems for oral lichen planus: a critical appraisal [PDF]
The aim of the present study has been to critically review 22 disease scoring systems (DSSs) on oral lichen planus (OLP) that have been reported in the literature during the past decades.
Van der Waal, Isaäc +3 more
core +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
Quantitative Expression of Cell-Free Salivary Transcriptomes (IL8, IL1β, And H3F3A) in Oral Squamous Cell Carcinoma and Oral Erosive Lichen Planus [PDF]
Objective: Diagnosis of oral SCC at its earliest stage is crucial for increasing survival rate. Salivary transcriptome meetsdemands for noninvasive, accessible, and highly efficient diagnostic medium.
Darya K. Mahmood +2 more
core +2 more sources
Metagenomic Evaluation of Oral Microbiota in Patients Affected by Oral Lichen Planus: A Pilot Study
ABSTRACT Objective To characterize the oral bacterial and fungal microbiota of symptomatic oral lichen planus patients undergoing topical corticosteroid therapy and to explore microbial patterns potentially associated with subsequent oral candidiasis. Methods Twelve patients with clinically and histologically confirmed OLP were enrolled.
A. Dormiente +5 more
wiley +1 more source
Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang +11 more
wiley +1 more source
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen +5 more
wiley +1 more source

