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Oral lichen planus: an overview
Lichen planus (LP) is a chronic inflammatory muco-cutaneous disease. Since disorders of NK-cell functional activity could be observed in patients with LP, it is considered to be an autoimmune disease. The pathogenesis of LP is complex and not completely understood.
Joachim Dissemond
exaly +3 more sources
Evaluation of Cyclooxygenase-2 in Oral Lichen Planus Using Immunohistochemistry [PDF]
Introduction: Lichen planus is a relatively common chronic inflammatory autoimmune disease of unknown etiology. The World Health Organization has identified lichen planus as a potential precancerous lesion.
Shadi Saghafi Khadem +2 more
doaj +1 more source
Introduction & Objectives: Lichen planus is a T-cell mediated chronic inflammatory mucocutaneous disease of unknown cause. Most dermatologists claim that 50 to 70% of their lichen planus patients have oral mucosal lesions, but oral pathologists usually report that relatively few of their patients (about 15%) have cutaneous lesions.
Marcello Menta Simonsen, Nico +2 more
+7 more sources
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age.[1][1],[2][2] Up to 77% of patients ...
Amr F, Hamour +2 more
openaire +2 more sources
Elevated Serum Interleukin-23 Levels in Patients with Oral and Cutaneous Lichen Planus
Lichen planus is considered a chronic inflammatory disease which affects different sites, such as the skin, mucous membranes, hair, and nails. Based on the evidence, a complex cytokine network plays a crucial role in lichen planus pathogenesis. The study
Maryam Mardani +4 more
doaj +1 more source
Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil. [PDF]
ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of
Biswas T +5 more
europepmc +2 more sources
Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus [PDF]
: Background: Oral lichen planus is a potentially malignant disorder. One of the malignant transformation markers is cancer stem cells. One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase.
Arash Mansourian +3 more
doaj +2 more sources
Oral lichen planus and its association with diabetes mellitus and hypertension
In 1963, Grinspan found an interesting association of oral lichen planus with diabetes mellitus and hypertension, which he called as Grinspan syndrome. Various studies carried later had ambigous findings.
Anjana Bagewadi, Anil Kumar Bhoweer
doaj +1 more source
Plethora of clinical forms exists in oral lichen planus (OLP), a common autoimmune disease involving mucous membrane. The commonest forms described in the literature are reticular, atropic, papular, bullous, plaque and erosive. The erosive type being the second most common, is a premalignant condition owing to its aggressiveness.
Pragadeesh Palaniappan +1 more
openaire +3 more sources
Evaluation of Salivary 8-Isoprostane in Oral Lichen Planus: Case Control Study
Introduction: Lichen planus is a chronic inflammatory disease that affects the skin, nails, and the mucous membrane and oral mucosal involvement may frequently precedes skin manifestation. It is hypothesized that free radicals and reactive oxygen species
Asha Sicily Dinesan, Rathy Ravindran
doaj +1 more source

