Results 231 to 240 of about 1,956,724 (307)

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Drug-Related Halitosis: A Narrative Review. [PDF]

Int Dent J
Iranitalab M, Ouanounou A.
europepmc   +1 more source

pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic Immunotherapy

Advanced Science, EarlyView.
A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li, Yun Li, Yating Hu, Yanbing Yao, Yaodong He, Jing Li, Jiaqi Tang, Zhenyan Zhao, Yan Wang, Yulun He, Xiaolong Zhang, Xinjie Yang, Jianhua Wei   +12 more
wiley   +1 more source

A Case-Based Literature Review of RELA Associated Inflammatory Diseases. [PDF]

J Clin Immunol
Karaçayır N, Yazol M, Yayla ENS, Şenol PE, Yıldız Ç, Belder N, Kutlar M, Küçükali B, Acun B, Yıldırım DG, Bakkaloğlu SA.   +10 more
europepmc   +1 more source

Oral literature : English

, 2015
openaire   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

On-target, off-tumor oral toxicities of talquetamab in heavily pretreated multiple myeloma. [PDF]

Support Care Cancer
Alves FA, Perez Perez A, Jaguar GC, Filho JS, Kim MK, Villa A.   +5 more
europepmc   +1 more source

Periodontitis and respiratory infections - exploring the oral-systemic link. [PDF]

Ann Med Surg (Lond)
Beniwal SS, Caroicar YS, Patil K, Rawat A, Said AS, Manickavelan HV, Desai A, Jani HT, Ribeiro da Costa REA, Cacas AC, Panjabi C, Dwivedi A.   +11 more
europepmc   +1 more source

Oral literature : Icelandic

, 2015
openaire   +1 more source