Results 41 to 50 of about 8,507,891 (284)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

How general dentists could manage a patient with oral lichen planus [PDF]

open access: yes, 2018
The literature hardly contains information on how patients suffering from oral lichen planus could be managed by dentists. Based on the limited available literature and particularly on the long-term clinical and histopathological experience of one of the
Robledo-Sierra, Jairo,   +8 more
core   +2 more sources

Sounds and sound thinking in |xam-ka !au: “These are those to which I am listening with all my ears”

open access: yesCogent Arts & Humanities, 2016
This paper questions preconceptions that situate the |xam in a Stone Age past where they can be objectified by a timeless gaze. From such appropriations and (miss)-representation, the |xam emerge either as shamans or victims or as the quintessential ...
Neil Rusch
doaj   +1 more source

Oral history, collective memory and socio-political criticism: A study of popular culture in Cameroon

open access: yesTydskrif vir Letterkunde, 2016
The growing popularity of contemporary Cameroonian popular cultural production is a significant indication of the value attached to the medium as well as the appreciation of the opportunity offered by the Biya regime.
Donatus Fai Tangem
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Literatura oral y política actual: el presidente Trump en la literatura de cordel brasileña

open access: yesBoletín de Literatura Oral, 2019
Since its origins, Brazilian Cordel Literature (chapbooks) was used as a news channel and as a means to discuss current political events in specific formats. Brazilian politics have always had priority in these texts.
Ricarda Musser
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Use of Bichat's buccal fat pad for the sealing of orosinusal communications. A presentation of 8 cases [PDF]

open access: yes, 2011
Objectives: To determine the efficacy of the pediculate flap with the buccal fat pad in the sealing of orosinusal communications, describe the surgical technique used, and report the main complications. Patients and method: A retrospective study was made
Figueiredo, Rui   +8 more
core   +1 more source

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