Results 111 to 120 of about 266,788 (256)

Allergic manifestations in oral cavity [PDF]

open access: yesActa Stomatologica Naissi, 2018
Introduction: An allergy is the failed defensive effort of the organism against foreign antigens. Reintroduction of the same foreign substance into the organism causes a reaction that leads to the destruction of one's own tissue.
Minić Ivan   +4 more
doaj  

Oral manifestations of primary immunodeficiencies

open access: yesБюллетень сибирской медицины, 2019
To understand the current state of the issue of dental manifestations of primary immunodeficiencies, foreign literature on the problem has been analyzed.
M. A. Dolgikh   +4 more
doaj   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

open access: yesAdvanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou   +22 more
wiley   +1 more source

Oral manifestations of viral infections

open access: yesSouth African Family Practice, 2006
Examination of the oral cavity in an integral part of every clinical examination. The clinical presentation of various viral conditions in discussed in this article and will provide the family practitioner with an up to date guide to better diagnosis and
W.F.P. van Heerden
doaj   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Recent syphilis with oral manifestations

open access: yesDST, 2018
Introduction: The occurrence of sexually transmitted infections with oral manifestations, such as syphilis, remains a challenge in the era of rapid tests associated with an adequate clinical evaluation in the patients’ approach.
Salvador Darcy da Silva   +8 more
doaj  

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

open access: yesAdvanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika   +22 more
wiley   +1 more source

Pyknodysostosis: Oral findings and differential diagnosis

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2008
Pyknodysostosis is a rare, genetic, autosomal recessive condition characterized by short stature, generalized bone sclerosis, and oral manifestations such as maxillary atresia and an increase of the mandibular angle.
Soares L   +3 more
doaj  

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

open access: yesAdvanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong   +13 more
wiley   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

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