Results 81 to 90 of about 189,784 (304)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Xerostomia, Salty Taste and Burning Mouth as Oral Manifestations of COVID-19

, 2022
Camilla Dos Santos, Estevam Rubens Utumi, Mrio Junior, Danilo Loureno, Irineu Gregnanin Pedron, Irineu Pedron, C Gaujac, I Pedron, C Shitsuka, Pedron Ig, B Iranmanesh, Santos Amorim Dos, Santos Amorim Dos   +12 more
openalex   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Data set - Oral manifestations associated with Novel Coronavirus Disease - 2019 (COVID -19): A questionnaire based hypothetical study

, 2022
Faraz Mohammed, Arishiya Thapasum Fairozekhan, Shamaz Mohamed, Saud Abdullah AlMoumen, Amr Bugshan, Zainab I. AlMomen, Aminah Mohammad AlMomen, Shashi Kiran M, Khalid S. Almulhim   +8 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Allergic manifestations in oral cavity [PDF]

Acta Stomatologica Naissi, 2018
Introduction: An allergy is the failed defensive effort of the organism against foreign antigens. Reintroduction of the same foreign substance into the organism causes a reaction that leads to the destruction of one's own tissue.
Minić Ivan, Pejčić Ana, Obradović Radmila, Mirković Dimitrije, Bradić Marija   +4 more
doaj  

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

Recent syphilis with oral manifestations

DST, 2018
Introduction: The occurrence of sexually transmitted infections with oral manifestations, such as syphilis, remains a challenge in the era of rapid tests associated with an adequate clinical evaluation in the patients’ approach.
Salvador Darcy da Silva, Gloria Iara dos Santos Barros, Alexandre Marques Paes da Silva, Tegnus Vinicius Depes de Gouvêa, Carla Renata Petillo de Pinho, Antônio Canabarro, Luiz Carlos Moreira, Dennis de Carvalho Ferreira, Mauro Romero Leal Passos   +8 more
doaj  

Unusual yet isolated oral manifestations of persistent thrombocytopenia: a rare case report [PDF]

, 2013
Amit Byatnal, Neha Mahajan, Shrinivas Koppal, A Ravikiran, R Thriveni, M Kamala Devi   +5 more
openalex   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source