Results 51 to 60 of about 2,083,027 (293)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Recycling the evidence: different approaches to the reanalysis of gerontological data [PDF]
, 2005 In 1991 Professor Margot JEFFERYS and two colleagues interviewed "pioneers of geriatric medicine" of whom 60 were geriatricians. These data are now on disk and can be searched digitally. The interviews were long and focussed on the careers of the doctors
Bornat, Joanna
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Integration-free reprogramming of lamina propria progenitor cells [PDF]
, 2016 Producing induced pluripotent stem cells (iPSCs) from human tissue for use in personalized medicine strategies or therapeutic testing is at the forefront of medicine.
Allen, Nicholas Denby +4 more
core +1 more source
Applied Medical Informatics, 2021 Introduction: Teledentistry is a widely accepted procedure for dental practice during the coronavirus disease 2019 (COVID-19) pandemic. Due to the nature of strict protocols that aims to prevent the transmission of the severe acute respiratory syndrome ...
Joshua MACAPAGAL +1 more
doaj
A multidisciplinary minimally invasive approach for the esthetics of the smile
Clinical Case Reports, 2021 The aim of this work is to define a new multidisciplinary pathway for dental and gingival problems. The method consists of three different instruments that can resolve dental, labial, and periodontal imperfections with minimal invasiveness.
Graziano Pallotta +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Dental Materials and Its Prospective Influence on Oral Mucosa
Česká Stomatologie a Praktické Zubní Lékařství, 2006 In view of the growing number and technological complexity of new dental materials it has become necessary to evaluate irritation and allergy potential of compound used in dentistry.
S. Kaprálová +4 more
doaj
Mandibular Bony Solitary Plasmacytoma: A Case Report
Clinical Case ReportsA hematologic malignancy should be considered in the differential diagnosis of any ulcerated multinodular oral mass.
Cyril Debortoli +3 more
doaj +1 more source
Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari +9 more
wiley +1 more source