Results 151 to 160 of about 370,051 (259)

An Interdisciplinary Role of Artificial Intelligence (AI) in Dentistry: A Focus on Endodontics, Oral Pathology, Prosthodontics, Orthodontics, and Periodontics. [PDF]

J Pharm Bioallied Sci
Sagare SV, Kumar P, Nayak R, Arya A, Patil A, Kaur M, Kaur G.   +6 more
europepmc   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Journey of Oral Pathology in India: Academics to Artificial Intelligence. [PDF]

J Oral Maxillofac Pathol
Tupkari JV.
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Prevalence and Clinico-Pathologic Profiles of Nonodontogenic Cysts of the Oral and Maxillofacial Region: A Multicentre Study

International Journal of Dentistry
Soranun Chantarangsu, Promphakkon Kulthanaamondhita, Kittipong Dhanuthai, Kraisorn Sappayatosok, Poramaporn Klanrit, Nutchapon Chamusri, Pouyan Aminishakib, Seyed Mohammdmoein Hosseini, Ripon Singh, Jannat Uddin, Mark Darling   +10 more
doaj   +1 more source

Artificial intelligence in systemic diagnostics: Applications in psychiatry, cardiology, dermatology and oral pathology. [PDF]

Bioinformation
Penhaskashi J, Danesh J, Naeim A, Golshirazi J, Hedvat J, Chiappelli F.   +5 more
europepmc   +1 more source

Recognition of Oral Pathology as a Subject among Dental Undergraduates: Addressing their Concerns.

J Pharm Bioallied Sci, 2023
Mahapatra KK, Mishra P, Adhikary T, Jha K, Barman D, Panda A.   +5 more
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Oral pathology in a population observed within an oral cancer screening developed in Portugal. [PDF]

Med Oral Patol Oral Cir Bucal
Pereira D, Andrade M, Moreira A, Caramês J, Pojo M, Freitas F.   +5 more
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source