Results 51 to 60 of about 86,974 (295)

Oral Potentially Malignant Disorders among Patients Attending the Department of Oral Medicine and Radiology of a Tertiary Care Dental Hospital: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Despite oral cancer being a common cancer in Nepal, little is known about oral potentially malignant disorders which have a high likelihood of malignant transformation.
Deepa Gurung, Ujjwal Joshi, Bikash Chaudhary, Preeti Singh   +3 more
doaj   +1 more source

Photodynamic therapy for oral potentially malignant disorders

Photodiagnosis and Photodynamic Therapy, 2019
To assess the impact of photodynamic therapy (PDT) parameters in the management of oral potentially malignant disorders (OPMDs). We conducted a systematic review and meta-analysis of studies that assessed the curative effect of PDT published in PubMed and Embase until Dec 2018.
Xin, Jin, Hao, Xu, Jing, Deng, Hongxia, Dan, Ping, Ji, Qianming, Chen, Xin, Zeng   +6 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Quantitative serum proteomic analysis among tobacco habitudes and oral potentially malignant disorders: A Case–control study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Oral cancer is the sixth most common cancer, with India having the largest burden. Oral potentially malignant disorders (OPMDs) refer to oral mucosal disorders with increased risk for malignancy.
Hemant Bhutani, Vasavi K Santosh, Sandeep Pagare, Anindya Kr Debnath, Mandavi Waghmare, Naveen Kumar Shetty   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Diagnosis of oral potentially malignant disorders: Overview and experience in Oceania

Frontiers in Oral Health, 2023
The diagnosis and management of oral potentially malignant disorders (OPMD) should be the same the world over, but there are important nuances in incidence, aetiological factors, and management opportunities that may lead to differences based on ...
Alison M. Rich, Haizal M. Hussaini, Muhammad Aiman Mohd Nizar, Ratu Osea Gavidi, Elizabeth Tauati-Williams, Muhammed Yakin, Benedict Seo   +6 more
doaj   +1 more source

Expression of S100A7 in oral potentially malignant disorders

Journal of Oral and Maxillofacial Pathology, 2022
Context: Oral potentially malignant disorders (OPMDs) are a group of heterogeneous lesions with an increased risk of malignancy. S100A7 expression serves as a biomarker to identify the dysplastic lesion. Aims: To study the status of S100A7 antigen in healthy oral mucosa and OPMDs.
Das, Pushpanjali, Deshmukh, Revati
openaire   +2 more sources

Potentially malignant disorders-The case for intervention [PDF]

, 2017
Potentially malignant disorders (PMD) are recognisable mucosal conditions preceding invasive squamous carcinoma development. Established oral cancer remains a lethal and deforming disease, with a rising incidence.
P. J. Thomson, Thomson, P.J., Thomson, PJ, Thomson, P. J.   +3 more
core   +1 more source