Results 171 to 180 of about 371,160 (303)

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

Oral History Interview, Patricia Kendall (2511)

open access: yes
In this interview, 14-year-old Eliot Kendall interviews her grandmother, Patricia Kendall, about Patricia’s experiences with energy sources and climate change as part of UW–Madison’s Grandparents University Renewable Energy Studies Major.
Kendall, Eliot, Kendall, Patricia
core  

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Mating type and genotyping of <i>Candida albicans</i> isolated from different samples. [PDF]

open access: yesIran J Microbiol
Karimpour A   +4 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

The Current State of Global Awareness and Knowledge on Oral Cancer: A Narrative Review. [PDF]

open access: yesHealth Sci Rep
Kanmodi KK   +5 more
europepmc   +1 more source

A meeting with the sources in History Oral

open access: yes, 2006
In this article we reflect upon the production and uses of sources and methodological tools which guide the actions of the historian who deals with the field conventionally referred to as Oral History. We aim at discussing the singularity of field work, bringing into play the relationship between the researcher and people who are listened to – a vital ...
openaire   +1 more source

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