Results 221 to 230 of about 1,275,299 (352)
Urbanization alters soil trace metal enrichment and health risks in the black soil Region of Northeast China. [PDF]
Du G +6 more
europepmc +1 more source
Halofuginone is a Molecular Glue Degrader of Integrin β4
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong +8 more
wiley +1 more source
Climate Variability, Urbanization, Water Insecurity, and Cholera in Somalia (2000-2025): A Thematic Narrative Review. [PDF]
Ahmed NI +6 more
europepmc +1 more source
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li +9 more
wiley +1 more source
Odontogenic Infection Associated with Facial Vascular Malformation: Diagnostic, Surgical, and Quality-of-Life Considerations That Should Not Be Overlooked. [PDF]
Nelke K +9 more
europepmc +1 more source
Voices from Within and Without: Sources, Methods, and Problematics in the Recovery of the Agrarian History of the Igbo (Southeastern Nigeria) [PDF]
Allison +57 more
core +2 more sources
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
Bilateral Cavernous Sinus Thrombosis Secondary to Dental Infection-Induced Sinusitis: A Case Report. [PDF]
Genkin M +4 more
europepmc +1 more source

