Results 251 to 260 of about 9,334,360 (340)

A new era in oral treatment for acromegaly with the FDA-approved drug paltusotine. [PDF]

Ann Med Surg (Lond)
Ahmed S, Asghar H, Khalid M.
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Comparative analysis of dental-derived stem cells and alternative stem cell sources: properties and regenerative functions. [PDF]

Front Bioeng Biotechnol
Yang K, Yuan S, Wang Y, Lin A, Huo F, Jin Z, Yang C, Tian W.   +7 more
europepmc   +1 more source

A Bear of a Case: Multidisciplinary Reconstruction Following a Grizzly Bear Mauling. [PDF]

Clin Case Rep
Beiriger J, Keefe KR, Tucker JR, Cannon RB, Adams D, McCrary HC.   +5 more
europepmc   +1 more source

Impact of drug shortages on the work of hospital pharmacists in Japan. [PDF]

J Pharm Policy Pract
Yasui T, Takase T, Ueno H, Kiko Y, Yamamuro F, Nakashima T, Muroi N.   +6 more
europepmc   +1 more source

Corrigendum to 'Comparison of direct oral anticoagulants and vitamin K antagonists in the treatment of left ventricular thrombi: a retrospective cohort study: [Research and Practice in Thrombosis and Haemostasis 9(7) 2025 103192]. [PDF]

Res Pract Thromb Haemost
Elbenawi H, Lipps K, Heller S, Liedl DA, Shields RC, Casanegra AI, Henkin S, Rooke TW, Wennberg PW, Wysokinski WE, McBane RD, Houghton DE.   +11 more
europepmc   +1 more source

Inadequate Micronutrient Intakes: Exploring the Vitamin and Mineral Intakes and Food Sources of New Zealand Aged-Care Residents. [PDF]

J Hum Nutr Diet
MacDonell SO, Miller JC, Fleming EA, Haszard JJ.   +3 more
europepmc   +1 more source

Tumor Location and Referral Sources as Determinants of Late-Stage Oral Cancer Diagnosis in a Portuguese Cohort. [PDF]

Cureus
Cunha Coutinho J, Cruz E Silva L, São João R, Cunha Coutinho G, Domingues T, Araújo Nobre M, Caldas C, Salvado F.   +7 more
europepmc   +1 more source