Results 111 to 120 of about 30,293 (303)

Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults [PDF]

, 2012
Background: The early detection and excision of potentially malignant disorders (PMD) of the lip and oral cavity that require intervention may reduce malignant transformations (though will not totally eliminate malignancy occurring), or if malignancy is ...
American Cancer Society, Barrellier, Barrellier, Bessell, Bhalang, Bowles, Brinkmann, Brocklehurst, Brocklehurst, Brocklehurst, Buchen, Chang, Chen, Conway, Csépe, Downer, Downer, Elango, Faggiano, Fedele, Ferlay, Fernández Garrote, Freedman, Furness, Garg, Glenny, Hapner, Holmstrup, Holmstrup, Holmstrup, Huber, Huff, Ikeda, Jaber, Jemal, Jullien, Jullien, Kulak, Landis, Lee, Leeflang, Leocata, Li, Lim, Lingen, Liu, Liu, Lodi, Macfarlane, Marzouki, Mashberg, Mashberg, Mathew, McGurk, Mehta, Moles, Nagao, Nagao, Nagao, Napier, Netuveli, Ogden, Oh, Parkin, Patton, Petti, Poh, Ramadas, Reibel, Rethman, Rogers, Rusthoven, Sankaranarayanan, Sankaranarayanan, Sankaranarayanan, Scott, Scully, Scully, Seoane Leston, Silverman, Speight, Srivastava, Su, Subramanian, Sweeny, Vacher, Vahidy, Vecchia, Waal, Warnakulasuriya, Warnakulasuriya, Warnakulasuriya, Warnakulasuriya, Warnakulasuriya, Warnakulasuriya, Whiting, Whiting, Wilson, Wyatt, Yusof   +99 more
core   +5 more sources

New Mechanisms for Regulation of Intracellular Collagen Degradation in Fibrotic Lesions of Periodontal Tissues

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Drug‐induced gingival overgrowth involves dysregulation of intracellular collagen degradation. The mechanisms that are involved in the regulation of lysosomal collagenolytic activity are poorly understood. Here, we focus on how cathepsins, Rabs, and V‐ATPases regulate intracellular collagen degradation and, in particular, the vesicular trafficking and ...
Wing Hei Wong, Ralph A. Zirngibl, Morris F. Manolson, Christopher A. McCulloch   +3 more
wiley   +1 more source

Loricrin expression and its implication in oral submucous fibrosis, hyperkeratosis and normal mucosa with association to habits – An immunohistochemical study

Journal of Oral Biology and Craniofacial Research, 2019
Objective: The coarse fibres of areca nut and the continuous friction from occluding teeth are major causes of mechanical stress to the oral mucosa in conditions like oral submucous fibrosis and frictional keratosis.
Nithya S, Elizabeth Joshua, Ranganathan K, Rooban Thavarajah, Umadevi K. Rao   +4 more
doaj   +1 more source

Estimation of Pyruvic acid in serum and saliva among healthy and potentially malignant disorder subjects – a stepping stone for cancer screening? [PDF]

, 2015
Background: According to Warburg’s effect, the rate of glycolysis increases in cancerous cells. This will increase overall levels of pyruvic acid. The present on-going study was conducted to estimate the levels of pyruvic acid in saliva and serum in ...
Acharya, Swathi, Bhat, Anithraj, Bhat, Manohara, Prasad, Kakarla, Trivedi, Dhiraj   +4 more
core   +1 more source

Roles of miR‐181 Family Members in OSCC: Implications for Therapy and Diagnostics

Cancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a common and aggressive form of head and neck cancer, frequently associated with smoking, alcohol consumption, and HPV infection. MicroRNAs (miRNAs) are small, non‐coding RNA transcripts that play significant roles in cancer initiation and progression.
Alexandra Iulia Aghiorghiesei, Andreea Nutu, Nikolay Mehterov, Christos K. Kontos, Boyan Vladimirov, Rares Buduru, Cornelia Braicu, Ioana Berindan‐Neagoe   +7 more
wiley   +1 more source

Spirulina and Pentoxyfilline – A Novel Approach for Treatment of Oral Submucous Fibrosis [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Oral submucous fibrosis is a habit associated insidious precancerous condition of the oral cavity commonly found in Asian countries. Many treatment modalities have been attempted in treating the condition apart from steroids which have ...
BHAVANA SUJANA MULK, PRASANNASRINIVAS DESHPANDE, NAGALAKSHMI VELPULA, VANI CHAPPIDI, RAJA LAKSHMI CHINTAMANENI, STUTI GOYAL   +5 more
doaj   +1 more source

Immunohistochemical study of Expression of Myofibroblasts in Oral Submucous Fibrosis, Oral Squamous Cell Carcinoma and Normal Mucosa [PDF]

, 2012
The aim of the study was to evaluate expression of myofibroblasts in oral submucous fibrosis, oral squamous cell carcinoma and normal mucosa. • In this study the immunohistochemical analysis was done with α-SMA (smooth muscle actin).
Sivachandran, A
core  

The PI3K/AKT/mTOR Pathway and Oral Diseases: A Bibliometric Analysis From 2008 to 2025

Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objectives The phosphoinositide 3 kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway is a key therapeutic target for oral diseases. This study uses bibliometric analysis to identify research trends, knowledge gaps, and the development of PI3K/AKT/mTOR‐targeted therapies.
Yena Gan, Duoduo Li, He Xu, Sheng Han, He Zhu, Zening Wei, Zhigang Cai, Jinwei Huang   +7 more
wiley   +1 more source

Is Chaalia/Pan Masala harmful for health? practices and knowledge of children of schools in Mahmoodabad and Chanesar Goth, Karachi [PDF]

, 2009
OBJECTIVE: To determine the practices and knowledge of harmful effects regarding use of Chaalia and Pan Masala in three schools of Mahmoodabad and Chanesar Goth, Jamshed Town, Karachi, Pakistan.
Qureshi, Riaz, Shah, Sameena, Syed, Iqbal Azam   +2 more
core   +1 more source

Autophagy mediates oral submucous fibrosis

Experimental and Therapeutic Medicine, 2016
Oral submucous fibrosis (OSF) is a chronic insidious disease of the oral mucosa, well-recognized as a premalignant condition and commonly found in Southern China. It is primarily caused by the habit of areca nut or gutkha chewing. OSF is believed to be a homeostatic disorder of the extracellular matrix and fibroblast proliferation.
Jiang, Li, Ting-Ting, Zhao, Peng, Zhang, Chao-Jin, Xu, Zhuo-Xiang, Rong, Zi-Yi, Yan, Chang-Yun, Fang   +6 more
openaire   +3 more sources