Results 61 to 70 of about 6,089 (206)

Comprehensive Integrated Single‐Cell and Spatial Transcriptomics Unveil the Dynamic Landscape of Betel Nut‐Associated Oral Mucosal Carcinogenesis and Its Tumor Microenvironment

MedComm, Volume 7, Issue 6, June 2026.
ABSTRACT Betel nut chewing is a major etiological factor for oral squamous cell carcinoma (OSCC), yet its mechanistic underpinnings remain poorly defined. Here, we performed single‐cell RNA sequencing and spatial transcriptomics from six OSCC patients to comprehensively dissect the tumor microenvironment (TME) dynamics and cellular heterogeneity ...
Wei Dong, Shuojin Huang, Yijun Wu, Congyuan Cao, Jiaxue Li, Qianting He, Anxun Wang   +6 more
wiley   +1 more source

Mastication and swallowing in patients with oral submucous fibrosis

, 2007
Objective: Early stages of oral submucous fibrosis may lead to masticatory and swallowing impairments. This study was, conducted to evaluate the masticatory and swallowing functions in a group of oral submucous fibrosis patients. Patients and Methods:
Yamada, Yoshiaki, Ariyawardana, Anura, Amarasena, Jayantha Kumari Chandrasekera, Amarasena, Najith   +3 more
core   +1 more source

Pathogenesis and therapeutic intervention of oral submucous fibrosis

Journal of Pharmacy and Bioallied Sciences, 2013
Oral submucous fibrosis (OSF) is a chronic, progressive, potentially malignant condition affecting the oral cavity and frequently involving the upper part of the aerodigestive tract including the oropharynx and the upper part of the esophagus.
Thukanaykanpalayam Ragunathan Yoithapprabhunath, Thangadurai Maheswaran, Janardhanam Dineshshankar, Abraham Anusushanth, Pandian Sindhuja, Govindasamy Sitra   +5 more
doaj   +1 more source

The Role of Chemopreventive Agents in the Management of Oral Potentially Malignant Disorders and Oral Cancer: A Narrative Review

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is a common and aggressive cancer sometimes subsequent to oral potentially malignant disorders (OPMDs). Notwithstanding progress in surgical, radiotherapeutic, and chemotherapeutic interventions, survival rates for OSCC continue to be inadequate and are associated with significant functional ...
Lana Sayal, Omar hamadah, Eyad Chatty, Anas Abdo, Sana Aghbari, Ali Munasser, Amirah Alnour   +6 more
wiley   +1 more source

Oral submucous fibrosis: Recent modalities of Treatment

, 2014
Oral submucous fibrosis is chronic progressive condition of oral cavity. It is characterized by progressive fibrosis of submucosal tissue. The condition is well recognized for its malignant potential.
Patel, Vishnu, Patel, Umesh
core   +1 more source

Oral Squamous Cell Carcinoma‐Risk Factors, Diagnosis, Treatment, and Prevention

Cancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of oral mucosa and accounts for approximately 90% of oral cancers. In‐depth understanding of pathogenesis, hallmarks, and etiological factors is a crucial prerequisite for advancing the diagnosis and treatment for OSCC patients. This review aims to present the
Liping Wang, Xiaole Liu, Mengjie Chen, Ying Hu, Lilei Zhu   +4 more
wiley   +1 more source

Role of Hemoglobin and Serum Iron in Oral Submucous Fibrosis: A Clinical Study

The Scientific World Journal, 2012
Background. Oral submucous fibrosis is a chronic, insidious oral mucosal condition affecting the most parts of the oral cavity with high malignant transformation rate triggered by areca nut chewing, nutritional deficiencies, immunologic processes, and ...
Hegde Karthik, Preeti Nair, Harshkant P. Gharote, Kavita Agarwal, Guruprasad Ramamurthy Bhat, Divyashree Kalyanpur Rajaram   +5 more
doaj   +1 more source

Proinflammatory cytokine levels in oral lichen planus, oral leukoplakia, and oral submucous fibrosis

, 2015
The objective of this study was to identify salivary and serum concentrations of interleukin (IL)-8, IL-6, and tumor necrosis factor alpha (TNF-α) in patients with oral lichen planus, oral leukoplakia, oral submucous fibrosis, and healthy controls.status:
Jacobs, Reinhilde, Kaur, Jasdeep
core   +1 more source

Prosthodontic rehabilitation of an edentulous patient affected with oral submucous fibrosis - A clinical report

SRM Journal of Research in Dental Sciences, 2012
Oral Submucous fibrosis is a precancerous condition affecting the oral cavity and sometimes the pharynx.In this case report, oral submucous fibrosis and related problems in prosthodontics rehabilitation and the techniques that improves the retention ...
M Mohammed Ibrahim, V Rangarajan, P B Yogesh, Mohamed A Riyaz, T Selvakumar   +4 more
doaj  

Oral cancer risk stratification: A cross‐sectional population‐based screening study in Northeast India

International Journal of Cancer, Volume 158, Issue 6, Page 1517-1527, 15 March 2026.
What's new? Oral cancer burden is high in India. Risk stratification for selection of high‐risk individuals could enable early detection through efficient screening programs. We conducted a cross‐sectional screening study in Northeast India to develop and validate an oral precancer/cancer risk prediction model.
Kunal Oswal, Satirtha Barman, Alexandar R. Kerr, Murad Zaman, Jnyanashree Patowary, Debasis D. Barali, Nipam Barman, Ashok Das, Umakant Nadkar, Rajesh Dikshit, Jennifer E. Gallagher, Mark W. Lingen, Richard Muwonge, Philip E. Castle, Li C. Cheung, Kelly J. Yu, Anil K. Chaturvedi, Arnie Purushotham   +17 more
wiley   +1 more source