Results 161 to 170 of about 939,947 (330)

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani   +11 more
wiley   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li   +9 more
wiley   +1 more source

Association of Infraorbital Nerve Injury with Zygomaticomaxillary Complex Fractures at a Tertiary Care Hospital, Karachi

open access: yesPakistan Journal of Medicine and Dentistry
Background: The zygomatic region stands out as the most prominent facial portion, and zygomatic complex fractures (ZMC) are the second most prevalent facial fractures in the lateral mid-face area.
Qasim Saleem   +5 more
doaj   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman   +6 more
wiley   +1 more source

Comparison of osseointegration in piezoimplants versus cylindrical implants [PDF]

open access: yes, 2019
BACKGROUND: Dental implants have been successful for the restoration of edentulous areas, but current techniques are inadequate in areas lacking sufficient bone volume. Piezoelectric surgery has shown encouraging effects on both osseous healing.
Fujinaka, Trevor
core  

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

The Importance of Maxillary Sinuses in Oral and Maxillofacial Surgical Procedures

open access: yes
Oral and maxillofacial surgical procedures, such as tooth extractions, surgical treatment of odontogenic maxillary sinus pathologies, dental implant surgery, orthognathic surgery, and sinus lift procedures, often correlate with the maxillary sinuses, due to anatomical proximity.
Gokhan, Gocmen,   +2 more
openaire   +2 more sources

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah   +3 more
wiley   +1 more source

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