Results 191 to 200 of about 203,188 (294)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Intraoral approach using CAD/CAM technology for the Dingman method: a case description. [PDF]

Quant Imaging Med Surg
Sugahara K, Ito K, Koyachi M, Hoshino T, Tachizawa K, Nakajima S, Aoki K, Matsunaga S, Odaka K, Katakura A.   +9 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Oral surgical procedures and prevalence of oral diseases in Oral Surgery Department in Faculty of Dentistry Sarajevo

, 2013
Sadeta Šečić, Samir Prohić, Sanja Komšić   +2 more
openalex   +2 more sources

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

A Cross-Sectional Survey of Dentists on Antibiotic Prescribing and Allergy Management in Oral Surgery. [PDF]

Oral Health Prev Dent
Golchini P, Behkar S, Kocamaz ÖF, Altundoğan S.   +3 more
europepmc   +1 more source

Major approaches oral cancer and bucomaxillofacial surgical procedures: a concise systematic review

Ricardo Barbosa de Freitas, Gisele Delmaschio Amigo Aredes, Igor Mariotto Beneti   +2 more
openalex   +2 more sources

To evaluate the Anesthetic efficacy of 0.75%, 0.50% and 0.20% ropivacaine without vasoconstrictor in the minor and major Oral and Maxillofacial Surgical procedures [PDF]

Jagriti Lahiri, Dev Garg, Arun Rai
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Clinical Significance of an Incidentally Detected Lateral Lingual Foramen on Cone-Beam Computed Tomography (CBCT): A Case Report and Review of Pertinent Literature. [PDF]

Cureus
Ramalingam S, Alamri AA, Almujali AA, Alqarni A, Alalwan AG, Alrefaei FM.   +5 more
europepmc   +1 more source